Sökning: "diabetes insulin"

Visar resultat 11 - 15 av 915 avhandlingar innehållade orden diabetes insulin.

  1. 11. Pathophysiology and treatment of defective insulin secretion in diabetes

    Författare :Anders Rosengren; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pancreatic beta-cells; stem cells; genetics; exocytosis; Adra2a; PACAP; GLP-1; Physiology; Fysiologi; secreting systems; Endocrinology; diabetology; Endokrinologi; insulin secretion; Diabetes mellitus; sekretion; diabetologi;

    Sammanfattning : Defective insulin secretion is a central feature in diabetes mellitus and results from reduced pancreatic beta-cell mass as well as aberrant beta-cell function. The pathophysiology of diabetes is incompletely known, but a strong hereditary component is suggested. LÄS MER

  3. 12. THE ROLE OF PHOSPHODIESTERASE 3B IN CAMP-MEDIATED REGULATION OF INSULIN SECRETION

    Författare :Helena Jones; Signaltransduktionsforskning; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; cAMP; PDE3B; exocytosis; insulin; diabetes; Medicine human and vertebrates ; Medicin människa och djur ; diabetologi; sekretion; Endokrinologi; diabetology; Endocrinology; secreting systems;

    Sammanfattning : Type 2 diabetes mellitus (T2DM) is characterized by various combinations of ?-cell failure and insulin resistance leading to hyperglycemia and glucose intolerance. In order to maintain glucose tolerance in the insulin resistance state, increased insulin secretion is a requirement and it is because of inadequate islet adaptation that glucose intolerance develops in T2DM. LÄS MER

  4. 13. Pathogenesis of type 2 diabetes -role of defects in insulin secretion and insulin sensitivity

    Författare :Devjit Tripathy; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; diabetology; Endokrinologi; sekretion; diabetologi; Endocrinology; secreting systems; Calpain 10 gene; genetics of type 2 diabetes; MODY; Endogenous glucose production; Disposition index; Botnia clamp; IGT; IFG; HOMA; insulin sensitivity; insulin secretion;

    Sammanfattning : Type 2 diabetes is characterised by defects in insulin sensitivity, insulin secretion and increased endogenous glucose production. The relative contribution of each of these defects remains controversial. LÄS MER

  5. 14. Ion channel control of phasic insulin secretion

    Författare :Xingjun Jing; Diabetes - öpatofysiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; phasic insulin secretion; Diabetes; pancreatic β-cells; ClC chloride channel; exocytosis; CaV channel;

    Sammanfattning : Glucose-stimulated insulin secretion exhibits a biphasic pattern. The mechanism underling biphasic insulin secretion is not fully understood, but consensus exists that an elevation in [Ca2+]i is required for both first- and second-phase insulin secretion. LÄS MER

  7. 15. Trials of Diets for Treatment of Diabetes : A comparison of diets for treatment of type 2 diabetes, aspects on long and short term effects

    Författare :Hans Guldbrand; Fredrik Nyström; Carl Johan Östgren; Staffan Lindeberg; Linköpings universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Dietary intervention; type 2 diabetes; low-carbohydrate diet; blood glucose; blood lipids; insulin; body mass index; quality of life; inflammation; cytokine;

    Sammanfattning : BackgroundType 2 diabetes is a common disease and the prevalence has increased in large parts of the world. In treatment of diabetes the type of diet is of great importance considering metabolic factors such as glucose level and blood lipids. LÄS MER