Sökning: "dhfr gene"
Visar resultat 1 - 5 av 7 avhandlingar innehållade orden dhfr gene.
Sammanfattning : Malaria-like parasites consist of a large group of species that infects primates, rodents, bats, lizard and birds. I have focused on parasites from the genera Haemoproteus, Plasmodium and Leucocytozoon that are infecting birds. LÄS MER
2. Drug discovery against leishmaniasis : Bio- and chemoinformatic guided strategies for target evaluation and hit identification
Sammanfattning : Leishmaniasis is a neglected tropical disease mainly affecting poor people in developing countries. It is caused by infections of flagellated protozoa belonging to genus Leishmania. The few available drugs are associated with problems such as low effectiveness, severe side effects and resistance development. LÄS MER
3. Molecular diagnosis of drug resistance in Plasmodium falciparum and virulence factors in Entamoeba histolytica
Sammanfattning : Four species of the protozoan parasite genus Plasmodiun are known to infect man. Plasmodium falciparum, the most virulent species is increasingly associated with resistance to antimalarial drugs. LÄS MER
4. Malaria on islands : human and parasite diversities and implications for malaria control in Vanuatu
Sammanfattning : The genetic diversities displayed by human and malaria parasites at different frequencies in different geographical areas represent a major obstacle for the development of malaria control strategies including malaria chemotherapy and malaria vaccine. We investigated some genetic diversities on Vanuatu islands with various malaria endemicities. LÄS MER
5. Characterization of resistance to quinolones, sulfonamide and trimethoprim in Campylobacter jejuni as well as to macrolides in the related bacterium, Helicobacter pylori
Sammanfattning : Gastroenteritis caused by C. jejuni is usually a mild to moderate self-limiting disease. Treatment is recommended in some cases. In recent years, quinolones have been increasingly used to treat acute bacterial enteritis. LÄS MER