Sökning: "dhea"

Visar resultat 1 - 5 av 22 avhandlingar innehållade ordet dhea.

1. 1. Clinical and experimental studies of organ-specific autoimmune diseases : With special reference to Addison's disease and autoimmune hepatitis : by Gennet Gebre-Medhin

   Författare :Gennet Gebre-Medhin; Uppsala universitet; []
   Nyckelord :Medical sciences; Addison s Disease; replacement therapy; DHEA; autoimmune hepatitis; APS I; autoantigen; cytochrome P4501A2; aromatic L-amino acid decarboxylase; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Organ-specific autoimmunity constitutes a large health problem, where both the clinical management and our understanding of the pathogenetic mechanisms need to improve. Women with Addison's disease have abnormally low levels of dehydroepiandrosterone (DHEA), its sulphate ester (DHEA-S) and androgens relative to age, and many patients complain of physical and mental fatigue and low stress tolerance. LÄS MER

3. 2. Stress Management Interventions and Predictors of Long-term Health : Prospectively Controlled Studies on Long-term Pain Patients and a Healthy Sample from IT- and Media Companies

   Författare :Dan Hasson; Ulla Maria Anderberg; Töres Theorell; Ulf Lundberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Social medicine; stress; health promotion; stress management; public health; psychosocial; self-rated health; pain; intervention; web; Internet; TNF-alpha; DHEA; NPY; CgA; Socialmedicin; Social medicine; Socialmedicin;

   Sammanfattning : This thesis reports on the effects of stress management on long-term pain patients and on a healthy sample from IT and media companies; two groups that are commonly exposed to high stress levels. Even if there are important differences between these two groups, there are similarities such as the necessity for effective stress management. LÄS MER

4. 3. Primary Sjögren´s Syndrome. Clinical Studies with reference to Hormonal Status, Psychiatric Symptoms and Well-Being

   Författare :Sigrídur Th. Valtýsdóttir; Uppsala universitet; []
   Nyckelord :Medical sciences; primary Sjögren´s syndrome; anxiety; depression; well-being; quality of life; hypothalamic-pituitary-thyroid-gonadal axis; androgens; MEDICIN OCH VÅRD; MEDICINE; MEDICIN; Medicine; medicin;

   Sammanfattning : Primary Sjögren's syndrome (pSS) is a chronic inflammatory connective tissue disease of unknown etiology. The disease primarily involves salivary and lacrimal glands which results in oral and ocular dryness (sicca symptoms). A wide spectrum of extraglandular features from various organs may be seen. LÄS MER

5. 4. Effect of pharmacological treatment of serotonergic function in depression

   Författare :Aram El Khoury; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Sertonin depression; platelets; HPA-axis; intracellular calcium; lithium; SSRI NRI;

   Sammanfattning : Since its identification in raphe neurons of the central nervous system (CNS), the biogenic amine serotonin (5- hydroxytryptamin, 5-HT) has been implicated in the etiology and pathophysiology of affective disorders, such as depression. It has been proposed that enhancement of central serotonergic transmission may underlie the therapeutic response to different types of antidepressant drugs. LÄS MER

7. 5. Neuroendocrine studies in suicide attempters and in hypersexual disorder

   Författare :Andreas Chatzittofis; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Early life adversity is associated with increased risk of high psychiatric disease, suicidal behavior as well as risky sexual behavior in adulthood. Altered functioning of several neurobiological systems, like the serotonergic system and the hypothalamic-pituitary-adrenal axis associated with suicidal behavior, may stem from both genetic and developmental causes. LÄS MER