Sökning: "developmental sequences"

Visar resultat 1 - 5 av 46 avhandlingar innehållade orden developmental sequences.

  1. 1. Mating type switching and transcriptional silencing in Kluyveromyces lactis

    Författare :Emad Barsoum; Åström Stefan; Laura Rusche; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Mating type switch; transcriptional silencing; alpha3; transposase; Ume6; Mts1; Ras; cAMP; K. lactis; Developmental biology; Utvecklingsbiologi; utvecklingsbiologi; Developmental Biology;

    Sammanfattning : To explore the similarities and differences of regulatory circuits among budding yeasts, we characterized the role of unscheduled meiotic gene expression 6 (UME6) and a novel mating type switching pathway in Kluyveromyces lactis. We found that Ume6 was required for transcriptional silencing of the cryptic mating-type loci HMLα and HMRa. LÄS MER

  3. 2. Epigenetic Regulation of the H19 Chromatin Insulator in Development and Disease

    Författare :Claes Holmgren; Rolf Ohlsson; Tomas Ekstöm; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Developmental Biology; Miljömedicinsk utvecklingsbiologi;

    Sammanfattning : The coordinated regulation of gene expression must be tightly controlled for normal development to occur. In mammals, this issue is further complicated by the requirement of both the maternal and paternal genomes for normal development, reflecting the fact that a subset of genes are monoallelically expressed depending on parental inheritance, a phenomenon known as genomic imprinting. LÄS MER

  4. 3. Erwerbsphasen, Entwicklungssequenzen und Erwerbsreihenfolge : Zum Erwerb der deutschen Verbalmorphologie durch schwedische Schülerinnen und Schüler

    Författare :Christine Fredriksson; Dieter Krohn; Britta Hufeisen; Uppsala universitet; []
    Nyckelord :German language; acquisition phase; developmental sequence; acquisition order; unanalysed routines; analysed routines; understanding; noticing; associative network; formal style; informal style; Tyska; German; tyska;

    Sammanfattning : The central theme of this work is the interaction and the influence of grammatical input as an external factor in language acquisition and in learning strategies and learning processes as cognitive requirements. Until now, this problem has been viewed from the perspective of explicit and implicit processes, including concepts such as consciousness/unconsciousness, outer rules/inner rules, and analysed/unanalysed knowledge. LÄS MER

  5. 4. Comparative Genomics of Obligate and Facultative Intracellular Parasites

    Författare :Cecilia Alsmark; Russell Regnery; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; molekylärbiologi; Molecular Biology;

    Sammanfattning : The α-proteobacteria Rickettsia prowazekii and Bartonella henselae are the causative agents of epidemic typhus and cat scratch disease respectively. Whereas R. prowazekii is an obligate intracellular parasite, B. henselae can live and proliferate both outside and inside the eukaryotic host cell. LÄS MER

  7. 5. Rates and Patterns of Mutation in Microsatellite DNA

    Författare :Jesper Brohede; Christian Schlötterer; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; evolutionär genetik; evolutionär genetik;

    Sammanfattning : Sequence comparisons of orthologous microsatellite loci in cattle and sheep revealed that the substitution rate in microsatellite flanking sequences does not differ from the rate in presumably neutrally evolving intron sequences. This suggests that microsatellites are generally located in regions that are not subjected to selection. LÄS MER