Sökning: "developmental processes"

Visar resultat 16 - 20 av 304 avhandlingar innehållade orden developmental processes.

1. 16. Genetic Disequilibria and the Interpretation of Population Genetic Structure in Daphnia

   Författare :Lars M. Berg; Xavier Vekemans; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; breeding system; linkage disequilibrium; dispersal; genetic structure; Daphnia pulex; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; naturvårdsbiologi; Conservation Biology;

   Sammanfattning : Understanding the processes that shape the spatial distribution of genetic variation within species is central to the evolutionary study of diversification and demography. Neutral genetic variation reflects past demographic events as well as current demographic characteristics of populations, and the correct interpretation of genetic data requires that the relative impact of these forces can be identified. LÄS MER

3. 17. Regulators of chromatin and transcription in Drosophila

   Författare :Filip Crona; Mattias Mannervik; Fernando Azorin; Stockholms universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Transcription; chromatin; co-regulators; CBP; lysine demethylase; KDM4A; Brakeless; Drosophila; utvecklingsbiologi; Developmental Biology;

   Sammanfattning : Development of multicellular organisms is achieved by organized temporal and spatial patterns of gene expression leading to cell differentiation. Chromatin regulators control how the DNA is utilized by altering access of proteins to DNA and thereby function as co-factors in transcription. LÄS MER

4. 18. Rates and Patterns of Mutation in Microsatellite DNA

   Författare :Jesper Brohede; Christian Schlötterer; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; evolutionär genetik; evolutionär genetik;

   Sammanfattning : Sequence comparisons of orthologous microsatellite loci in cattle and sheep revealed that the substitution rate in microsatellite flanking sequences does not differ from the rate in presumably neutrally evolving intron sequences. This suggests that microsatellites are generally located in regions that are not subjected to selection. LÄS MER

5. 19. Adrenal Bioactivation and Toxicity of 3-MeSO2-DDE, o,p´-DDD and DMBA Investigated in Tissue Slice Culture

   Författare :Örjan Lindhe; Jan Alexander; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; adrenal cortex; 3-MeSO2-DDE; o; p´-DDD; DMBA; bioactivation; binding; toxic; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; Ecotoxicology; ekotoxikologi;

   Sammanfattning : I developed a precision-cut adrenal slice culture procedure to investigate cytochrome P450 (CYP) catalysed irreversible binding and adrenocorticolytic effects in human, rodent, and fish adrenal tissue, ex vivo. Autoradiography and radioluminography of exposed tissue slices showed that the potent adrenal toxicant 3-methylsulphonyl-2,2´-bis(4-chlorophenyl)-1,1´-dichloroethene (MeSO2-DDE) causes a selective metabolite binding in zona fasciculata (ZF), which is diminished by the CYP11B1 inhibitor metyrapone. LÄS MER

7. 20. Trade-off between starvation and predation : Weight-watching in Yellowhammers

   Författare :Ineke T. van der Veen; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Developmental biology; Utvecklingsbiologi; Developmental biology; Utvecklingsbiologi; populationsbiologi; Population Biology;

   Sammanfattning : In this thesis I show that captive yellowhammers (Emberiza citrinella) strategically adjusted their level of body mass and diurnal trajectory of mass increase to experimentally increased predation risk. During winter, small birds need large fat reserves to survive the night. Therefore, they build up fat reserves every day. LÄS MER