Sökning: "desolvation"
Visar resultat 1 - 5 av 10 avhandlingar innehållade ordet desolvation.
1. From Solution into Vacuum - Structural Transitions in Proteins
Sammanfattning : Information about protein structures is important in many areas of life sciences, including structure-based drug design. Gas phase methods, like electrospray ionization and mass spectrometry are powerful tools for the analysis of molecular interactions and conformational changes which complement existing solution phase methods. LÄS MER
2. Analysis of lignin monomers and oligomers in technical lignins using chromatography and mass spectrometry
Sammanfattning : Lignin is the most abundant aromatic biopolymer on earth and has the potential to play an important role in the transition from an oil-based refinery to a biorefinery-based industry. The isolation of lignin from the biomass can be achieved by several different technical processes and isolated lignins are referred to as technical lignins in literature. LÄS MER
3. Coarse-Grained Models of Ionic Solutions
Sammanfattning : Room-temperature ionic liquids (RTILs) are compounds composed entirely of ions, which are liquid at temperatures below 100 degrees Celsius. Their high ionic strength and strong coupling make them useful for a number of applications, e.g. as electrolytes in supercapacitors. LÄS MER
4. From Structure to Function with Binding Free Energy Calculations for Codon Reading, Riboswitches and Lectins
Sammanfattning : Molecular association is part of many important processes in living cells. Computational methods for calculating binding free energies allows for a quantitative examination of biomolecular structures and hypotheses drawn from biochemical experiments. LÄS MER
5. Development and evaluation of analytical techniques for antibodies and antibody-drug conjugates : From verification of conjugation to stability testing
Sammanfattning : Antibody-drug conjugates (ADCs) are becoming increasingly important in oncology. ADCs are inherently heterogeneous analytes. For a successful drug candidate to go through to the clinic, extensive characterization and evaluation of the constructs are necessary. LÄS MER