Sökning: "depression subtype"

Visar resultat 1 - 5 av 22 avhandlingar innehållade orden depression subtype.

  1. 1. Cultural explanatory models of depression i Uganda

    Författare :Elialilia Sarikiaeli Okello; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Depression; depression subtype; psychotic depression; culture; cultural competence; emic; etic; explanatory models; case vignette; qualitative research; help seeking; pathway to care; indigenous model; traditional healer; health policy.;

    Sammanfattning : Background: Depressive disorders are among the most frequent psychiatric disorders, accounting for up to 30% of primary care service utilisation in developing countries in general, and Uganda in particular. However, delays in seeking treatment, misdiagnosis and non-specific treatments have compromised appropriate care for people with depression. LÄS MER

  3. 2. Brain galanin sytems and their role in depression-like behaviour

    Författare :Eugenia Kuteeva; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :5-HT1A receptor; depression-like behaviour; forced swim test; galanin; galanin-overexpressing; galanin receptor; noradrenaline; serotonin; transgenic mouse;

    Sammanfattning : The aim of the present thesis was to investigate the role of the neuropeptide galanin and galanin receptor subtypes in behavioural functions with a particular focus on depression-like behaviour. In agreement with its wide distribution in the central nervous system, galanin has been implicated in various functions, including regulation of reproduction, endocrine functions, antinociception, attention, learning and memory as well as regulation of mood. LÄS MER

  4. 3. Serotonin in emotional memory processes : neuropharmacological studies with emphasis on depression

    Författare :Therese M Eriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Cognitive dysfunctions are common in neuropsychiatric disorders including Major Depressive Disorder, but are difficult to normalize by antidepressant therapies and contribute to reduced functional improvement. Cognitive impairments include alterations of emotional memory processes that are early targeted by antidepressant therapies, including Selective Serotonin Reuptake Inhibitors (SSRIs). LÄS MER

  5. 4. Juvenile idiopathic arthritis - from macrophage to mortality

    Författare :Elisabet Berthold; Reumatologi och molekylär skelettbiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Juvenile idiopathic arthritis; Epidemiology; outcome evaluation; Monocytes; Inflammation; Depression and Anxiety;

    Sammanfattning : Juvenile idiopathic arthritis (JIA) is the most common rheumatic disease in children. Studies of the immunopathogenesis in JIA has mainly focused on the adaptive immune system, while less is known of the role of the monocytes. LÄS MER

  7. 5. Estrogen receptor gene activity within the brain and the relation to psychiatric disorders : mapping and function

    Författare :Marie Österlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :steroid hormone; ER system; in situ hybridization; rnRNA; ER serotonin; depression; affective disorders;

    Sammanfattning : Estrogens have for a long time been known to regulate neuroendocrine functions in the central nervous system (CNS), primarily related to reproduction. In recent years estrogens have been found to also modulate many other brain functions, for example mood and cognition. LÄS MER