Sökning: "deoxyribonucleotides"
Visar resultat 1 - 5 av 28 avhandlingar innehållade ordet deoxyribonucleotides.
1. Cloning and characterization of human deoxyribonucleoside kinases : phosphorylation of anti-cancer and anti-viral nucleoside analogs
Sammanfattning : Deoxyribonucleoside kinases catalyze the phosphorylation of deoxyribonucleosides to deoxyribonucleoside monophosphates. There are four major deoxyribonucleoside kinasesin human cells: thymidine kinase 1 (TKl), deoxycytidine kinase (dCK), deoxyguanosinekinase (dGK), and thymidine kinase 2 (TK2). LÄS MER
2. The influence of nucleotides on ribonucleotide reductase assambly in class I ribonucleotide reductase from Escherichia coli
Sammanfattning : The components of DNA, the deoxyribonucleotides, are produced from the components of RNA, the ribonucleotides. One single substitution is needed to convert a ribonucleotide into a deoxyribonucleotide i.e. a replacement of a hydroxyl group with a hydrogen atom. LÄS MER
3. Allosteric Regulation and Radical Transfer in Ribonucleotide Reductase
Sammanfattning : The stability of biological life over time requires that the integrity of the genetic material of an organism, the genome, be maintained as it is passed on from one generation to the next. All known cellular life has DNA-based genomes, which are duplicated before each cell division in a process called replication. LÄS MER
4. To reduce a ribonucleotide – Radical solutions in enzymology in form and function
Sammanfattning : It has been more than 50 years since the enzyme system ribonucleotide reductase (RNR), catalysing the reduction of ribonucleotides to deoxyribonucleotides, was first discovered. RNR was also the first time that radical chemistry was revealed in an enzyme. LÄS MER
5. Activation, reaction mechanism and allosteric regulation of the anaerobic ribonucleotide reductase from bacteriophage T4
Sammanfattning : Ribonucleotide reductase (RNR) catalyse the conversion of ribonucleotides to their corresponding deoxyribonucleotides in all organisms. The deoxyribonucleotides are the building blocks for DNA. Three different classes of RNR are found, class I, II and III. LÄS MER