Sökning: "den medicinska modellen"

Visar resultat 1 - 5 av 36 avhandlingar innehållade orden den medicinska modellen.

  1. 1. Monoglyceride Lipase and Hormone-Sensitive Lipase - Molecular and structural aspects

    Författare :Marie Karlsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; genomic organisation; baculovirus-insect cells; catalytic triad; alfa beta hydrolase fold; tissue distribution; cDNA sequence; lipolysis; adipocyte; monoglyceride lipase; hormone-sensitive lipase; chromosomal localisation; Clinical biology; Klinisk biologi;

    Sammanfattning : Triglycerides in the adipocyte are hydrolysed by means of three consecutive reactions through the combined action of two lipases: hormone-sensitive lipase (HSL) and monoglyceride lipase (MGL). HSL catalyses the first and rate-limiting step, i.e. LÄS MER

  3. 2. Capillary and interstitial transport of fluid and solutes across the peritoneal membrane

    Författare :Ola Carlsson; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vascular resistance.; capillary pressure; aquaporins; Capillary permeability; vesicular transport; Urology; nephrology; Urologi; nefrologi;

    Sammanfattning : According to the three-pore model of peritoneal transport the major exchange pathway between the blood and the peritoneal cavity is represented by “small pores”, permeable to small solutes and water. Osmotically induced fluid flow, as during peritoneal dialysis (PD), is postulated to occur to a great extent through a water-only pathway, whereas proteins are predicted to reach the peritoneal cavity by unidirectional convection across “large pores”. LÄS MER

  4. 3. Extracellular Matrix Remodelling-Proteoglycan and collagen turnover in arthritis

    Författare :Anette Bjärdahlen; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Arthritis; collagen; cartilage; myofibroblasts; pannus; proteoglycan; Skeleton; muscle system; rheumatology locomotion; reumatologi; Skelett; muskelsystem;

    Sammanfattning : Rheumatoid arthritis is a chronic, inflammatory and systemic disease characterised by joint destruction and pannus formation. To enlarge the understanding how pannus and granulation tissue are formed two animal models were used; one using cartilage wrapped in cotton and implanted into a rat air pouch (AP) and one where mBSA induced arthritis (AIA) was performed. LÄS MER

  5. 4. Mucins in normal and diseased airways

    Författare :Hans Hovenberg; Institutionen för experimentell medicinsk vetenskap; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Respiratory system; Submucosal glands; Goblet cells; Organ culture; Respiratory tract; Mucins; Mucus glycoproteins; Andningsorganen;

    Sammanfattning : Mucus glycoproteins (mucins) are the principal constituents of respiratory secretions in health and disease. The increased 'acidity' of mucin producing cells in the bronchitic airways is not reflected in a change of negative charge of bronchitic mucins. LÄS MER

  7. 5. New models for relapsing polychondritis and rheumatoid arthritis : focus on the tissue specific immune response

    Författare :Ann-Sofie Hansson; Immunologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; relapsing polychondritis rheumatoid arthritis matrilin-1 collagen model; Clinical biology; Klinisk biologi;

    Sammanfattning : Relapsing polychondritis (RP) and rheumatoid arthritis (RA) are autoimmune diseases where an inappropriate immune response destroys cartilage. In RP, the ears, larynx, nose and joints are affected, while the most prominent sign of RA is arthritis. LÄS MER