Avancerad sökning

Hittade 5 avhandlingar som matchar ovanstående sökkriterier.

1. 1. Basic fibroblast growth factor for stimulation of bone formation in osteoinductive and conductive implants

   Författare :Jian-Sheng Wang; Lund Ortopedi; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Biofysik; Biophysics; bone ingrowth; titanium chamber; hyaluronic acid; porous hydroxyapatite; bone graft; bFGF; demineralized bone matrix; orthopaedics; traumatology; Kirurgi; ortopedi; traumatologi;

   Sammanfattning : Basic Fibroblast Growth Factor (bFGF) is one of the endogenous factors found in bone matrix. bFGF is a mitogen for many cell types, including osteoblasts and chondrocytes. It can stimulate angiogenesis and osteoblast gene expression. LÄS MER

3. 2. Expression and localization of extracellular matrix proteins in rat skeletal development

   Författare :Zhenxin Shen; Institutionen för experimentell medicinsk vetenskap; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BSP and osteoadherin.; COMP; chondroadherin; rat femoral head; Bone; extracellular matrix protein; cartilage; Skeleton; muscle system; rheumatology locomotion; Skelett; muskelsystem; reumatologi;

   Sammanfattning : Several novel matrix molecules of cartilage and bone have recently been identified and characterized. Studies of the maturation of the femoral head give clues as to the function of the novel matrix proteins. LÄS MER

4. 3. The effects of cyclosporin A on bone turnover and repair

   Författare :Anders Ekelund; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Cyclosporin A; osteoinduction; osteoconduction; bone turnover; fracture healing; Kirurgi; Surgery; Kirurgi; Orthopaedics; ortopedi;

   Sammanfattning : The effects of cyclosporin A on bone metabolism are unclear and controversial. The aims of this thesis were to study the effects of cyclosporin A on bone turnover and on different repair processes such as fracture healing, osteoinduction and osteoconduction. LÄS MER

5. 4. Insulin-like growth factor-I from a perspective of bone regeneration

   Författare :Per Prisell; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :insulin-like growth factor-I; fracture healing; endochondral bone formation; slow release; indomethacin; corticosteroids; hyaluronan; von Kossa;

   Sammanfattning : The insulin-like growth factor I (IGF-I) is produced by osteoblasts and many other cell types. IGF-I is abundant in bone matrix and mediates some of the effects of growth hormone (GH). The present investigations have focused on IGF-I actions during bone regeneration. LÄS MER

7. 5. Heterotopic Ossification : Clinical and Experimental Studies on Risk Factors, Etiology and Inhibition by Non-steroidal Anti-inflammatory Drugs

   Författare :Per-Erik Persson; Olle Nilsson; Per Aspenberg; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Surgery; Heterotopic ossification; Hip prosthesis; NSAIDs; Prophylaxis; Prosthesis loosening; Reoperation; Animal model; Bone formation; Kirurgi; Surgery; Kirurgi;

   Sammanfattning : In this thesis, occurrence of heterotopic ossification (HO) following total hip arthroplasty (THA) was studied. Preventive effects and complications with non-steroidal anti-inflammatory drugs (NSAIDs) were analyzed. Experimental investigations on bone formation were employed to gain insight to the mechanism of NSAIDs action on bone.(I). LÄS MER