Sökning: "demethylation"
Visar resultat 1 - 5 av 44 avhandlingar innehållade ordet demethylation.
1. Mercury species transformations in marine and biological systems studied by isotope dilution mass spectrometry and stable isotope tracers
Sammanfattning : This thesis focuses on the implementation of species-specific isotope dilution (SSID) methodology and stable isotope tracers to determine mercury species occurrence and transformation processes in-situ and during sample treatment. Isotope enriched tracers of methyl-, ethyl- and inorganic mercury were synthesised and applied in different combinations to marine and biological samples. LÄS MER
2. Unraveling the importance of solid and adsorbed phase mercury speciation for methylmercury formation, evasion and bioaccumulation
Sammanfattning : Monomethylmercury, MeHg, is formed under anoxic conditions in waters, sediments and soils and then bioaccumulated and biomagnified in aquatic food webs, negatively effecting both human and wildlife health. It is generally accepted that precipitation of mercury, Hg, and adsorption of Hg to e.g. LÄS MER
3. Formation, uptake and bioaccumulation of methylmercury in coastal seas : a baltic sea case study
Sammanfattning : Methylmercury (MeHg) is a potent neurotoxin which can bioaccumulate to harmful levels in aquatic food webs. Methylmercury formation is a predominantly biotic process which involves phylogenically diverse microorganisms (e.g. iron- or sulfate-reducing bacteria). LÄS MER
4. Studies of Budding Yeast Transcription Factors Acting Downstream of Nutrient Signaling Pathways
Sammanfattning : Being able to respond to extracellular cues such as nutrients and growth factors is of vital importance to all living cells. Pathways have therefore evolved which can sense the extracellular status, transmit a signal through the cell and affect gene expression, which ultimately enables adaptation. LÄS MER
5. Formation of active metabolites by demethylation and hydroxylation of tricyclic antidepressants in man
Sammanfattning : .... LÄS MER