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1. 1. Hepatic 3D spheroids as a model system for drug-induced liver injury and cytochrome P450 induction

   Författare :Delilah F G Hendriks; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Drug-induced liver injury (DILI) is a major cause of post-marketing drug withdrawals and restricted-use warnings. In addition, unexpected adverse hepatic drug reactions occurring in the clinical phases of development are a major reason for drug attrition. LÄS MER