Sökning: "dehydroepiandrosterone"

Visar resultat 1 - 5 av 32 avhandlingar innehållade ordet dehydroepiandrosterone.

  1. 1. Clinical and Experimental Studies in Primary Sjögren’s Syndrome and Systemic Lupus Erythematosus

    Författare :Gunnel Nordmark; Lars Rönnblom; Olle Kämpe; Ola Winqvist; Lennart Jacobsson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Medicine; Sjögren’s syndrome; SLE; α-fodrin; interferon-α; single nucleotide polymorphism; dehydroepiandrosterone; Medicin; Dermatology and venerology; clinical genetics; internal medicine; Dermatologi och venerologi; klinisk genetik; invärtesmedicin;

    Sammanfattning : Autoimmune mechanisms and genetic susceptibility contribute to the pathogenesis of primary Sjögren’s syndrome and SLE. These chronic systemic autoimmune diseases have many serological and clinical features in common and have an impact on daily life. LÄS MER

  3. 2. Hormonal programming and adrenal function. Studies in children and in a rat model

    Författare :Jovanna Dahlgren; Göteborgs universitet; []
    Nyckelord :Children; cortisol; dehydroepiandrosterone sulphate; small for gestational age; short stature; cytokines; dexamethasone; insulin sensitivity; androgenization;

    Sammanfattning : Prenatal events during specific time windows have been found to be followed by permanent changes affecting neuroendocrine, so called programming. Undernutrition, placental dysfunction or maternal stress, are apparent examples of such stimuli. LÄS MER

  4. 3. Health changes in a market changing labour market

    Författare :Hugo Westerlund; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Personnel Downsizing; Personnel Expansion; Labour market exit; Labour market programme; Unemployment; Occupational Health; Personnel Staffing and Scheduling; Sick Leave statistics numerical data; Hospitalization statistics numerical data; Triglycerides; Cholesterol; Fibrinogen; Prolactin; Dehydroepiandrosterone Sulfate; Blood pressure; Stress; Psychological metabolism; Sweden.;

    Sammanfattning : The late 20th century saw major changes in working life across the world. In Sweden, the changes on the labour market had a very strong impact in the early years of the 1990s. LÄS MER

  5. 4. The limbic-hypothalamic-pituitary-adrenal axis in Alzheimer's disease

    Författare :Birgitta Näsman; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Alzheimer’s disease; multi-infarct dementia; hippocampus; temporal lobe; adrenal androgens; adrenocorticotropin; corticotropinreleasing hormone; cortisol; skin blanching;

    Sammanfattning : Dysfunction of the limbic-hypothalamic-pituitary-adrenal (LHPA) axis is a common finding in advanced dementia. In this study, the function of the LHPA axis at different levels was investigated in patients with dementia and in healthy elderly.A subtle disturbance in the feedback regulation of the LHPA axis was found in patients with early (i.e. LÄS MER

  7. 5. Cytochrome P450 Enzymes in the Metabolism of Cholesterol and Cholesterol Derivatives

    Författare :Maria Norlin; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Pharmaceutical biosciences; Farmaceutisk biovetenskap; Biopharmacy; Biofarmaci; farmaceutisk biokemi; Pharmaceutical Biochemistry;

    Sammanfattning : Cholesterol is metabolized to a variety of important biological products in the body including bile acids and vitamin D. The present investigation is focused on enzymes that catalyze 7α-hydroxylation or 27-hydroxylation in the metabolism of cholesterol, oxysterols (side chain-hydroxylated derivatives of cholesterol) and vitamin D3. LÄS MER