Sökning: "degrees-c"

Visar resultat 1 - 5 av 16 avhandlingar innehållade ordet degrees-c.

1. 1. Structure determination, thermal stability and catalytic mechanism of hyperthermostable isocitrate dehydrogenases

   Författare :Mikael Karlström; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :X-ray crystallography; isocitrate dehydrogenase; thermostability; catalytic mechanism;

   Sammanfattning : In this thesis, studies on the enzyme isocitrate dehydrogenase (IDH) from the hyperthermophiles Aeropyrum pernix (ApIDH), Thermotoga maritima (TmIDH), Archaeoglobus fulgidus (AfIDH) and Pyrococcus furiosus (PfIDH) are presented. The aim of the described work was to contribute to the understanding of protein thermostability and to study the catalytic mechanism. LÄS MER

3. 2. Chemical emissions from concrete

   Författare :Kristina Hjellström; Avdelningen för Byggnadsmaterial; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; miljöpåverkan; mätmetoder; emissioner; flyktiga organiska föroreningar; betong; VOC; emissionsmätningar;

   Sammanfattning : The major part of this work deals with a new method for quantification of VOCs in concrete. There is a need for this type of quantification due to the development in cement and concrete production using plasticizing agents and fillers for improved rheological properties, and alternative fuels and waste materials to reduce the environmental impact of cement production. LÄS MER

4. 3. Bleeding and hemostasis during normo- and hypothermia : studies on porcine and rat models

   Författare :Göran Heinius; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Background: Numerous animal studies have shown protective effects of hypothermia (HT) on hemorrhagic shock. These findings do not correlate with clinical findings, were studies on trauma registers have shown that HT is an independent factor of death when associated with trauma. LÄS MER

5. 4. PWO Crystal Measurements and Simulation Studies of Anti-Hyperon Polarisation for PANDA

   Författare :Sophie Grape; Tord Johansson; Thomas Nilsson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PANDA; PWO; antiproton; hyperon; polarisation; Nuclear physics; Kärnfysik; Kärnfysik; Nuclear Physics;

   Sammanfattning : The Gesellschaft für Schwerionenforschung (GSI) facility in Darmstadt, Germany, will be upgraded to accommodate a new generation of physics experiments. The future accelerator facility will be called FAIR and one of the experimentsat the site will be PANDA, which aims at performing hadron physics investigations by colliding anti-protons with protons. LÄS MER

7. 5. Syntheses of some tri- and tetracyclic heterocycles containing an indole moiety

   Författare :Robert Engqvist; jan Bergman; Victor Snieckus; Södertörns högskola; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Alkaloid; drug development; heterocycles; indole; metabolite; synthesis; X-ray crystallography;

   Sammanfattning : This thesis deals with the development of new synthetic methods leading to fused tri- and tetracyclic heterocycles, many of which have interesting biological activity such as antiviral and DNA intercalating properties. The reactions between isatins and 2-aminobenzylamine in acetic acid can give, depending on the conditions, either complex spirooxindoles or indolo[3,2-c]quinolin-6-ones. LÄS MER