Sökning: "degradable porous scaffold"

Visar resultat 1 - 5 av 11 avhandlingar innehållade orden degradable porous scaffold.

  1. 1. Porous degradable polyester scaffolds

    Författare :Peter Plikk; Ann-Christine Albertsson; Johan Lind; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; aliphatic polyester; copolymer; porous scaffold; ring-opening polymerization; electron beam; gamma irradiation; Polymerteknologi; Chemistry; Kemi;

    Sammanfattning : Tissue engineering is a growing research field in which degradable porous scaffolds are used to regenerate tissue from the patients own cells. The problems due to donor shortage or the lack of full property restoration from prosthetic implants can thereby be overcome. LÄS MER

  3. 2. Design of Functional Degradable Aliphatic Polyesters and Porous Tissue Engineering Scaffolds

    Författare :Peter Plikk; Ann-Christine Albertsson; Marek Kowalczuk; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ring-opening polymerization; Stannous octoate; 2; 2’-azoisobutyronitrile; 1; 5-dioxepane-2-one; ε-caprolactone; L-lactide; Trimethylene carbonate; 2-methylene-1; 3-dioxe-5-pene; Copolymer; Porous scaffold; Porous tubular scaffold; Electron beam; Gamma irradiation; Polymer chemistry; Polymerkemi;

    Sammanfattning : The regeneration of damaged tissues or organs using porous scaffolds which act as temporary guides for the patient’s own cells, i.e. tissue engineering, is a means to overcome the shortcomings of current standard medical treatments. LÄS MER

  4. 3. Macromolecular synthesis of functional degradable aliphatic polyesters and porous scaffold design

    Författare :Sofia Målberg; Ann-Christine Albertsson; Anders Södergård; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; functional polyesters; condensation polymerization; L-lactide; ε-caprolactone; triblock copolymer; mechanical properties; porous scaffolds; tissue engineering; ring-opening polymerization; Bi III acetate; creatinine; stannous 2-ethylhexanoate; enzyme; degradation products; Polymer chemistry; Polymerkemi;

    Sammanfattning : There is an increasing demand for new materials in biomedical applications with material properties that are highly specific for each application area. The search for new materials requires the creation of materials with suitable mechanical properties, functionalities, three-dimensional structures and a controlled degradation profile. LÄS MER

  5. 4. degradable electroactive polymers: Synthesis, Macromolecular architecture and scaffold design

    Författare :Baolin Guo; Ann-Christine Albertsson; Patric Jannasch; KTH; []
    Nyckelord :Poly lactide ; poly ε-caprolactone ; ring-opening polymerization; carboxyl-capped aniline trimer; carboxyl-capped aniline pentamer; phenyl amino-capped aniline tetramer; coupling reaction; DCC DMAP system; degradability; electroactivity; conductivity; macromolecular architecture; chitosan; hydrogel; block copolymer; functionalization; oxidative coupling reaction; self-assembly; toxicity; tubular porous scaffold; neural tissue engineering.;

    Sammanfattning : Electrically conducting polymers induce specific cellular responses at the molecular level. One of the crucial limitations of the use of conducting polymers in tissue engineering is their inability to degrade. LÄS MER

  7. 5. Synthesis of Biomedical Polymers and Scaffold Design

    Författare :Therese Tyson; Ann-Christine Albertsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; ring-opening polymerization; tin alkoxide initiator; stannous octoate; poly p-dioxanone ; copolymer; L-lactide; trimethylene carbonate; degradable porous scaffold; Polymer chemistry; Polymerkemi;

    Sammanfattning : This work has focused on the development of new improved synthesis methods of biodegradable aliphatic polymers and on the preparation of porous scaffolds for tissue engineering applications. The aim of the first part of the work was the synthesis of poly(p-dioxanone) (PPDX) homopolymers with high molecular weights using the cyclic tin alkoxide initiator 1-di-n-butyl-1-stanna-2,5-dioxacyclopentane. LÄS MER