Sökning: "degradable polyesters"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden degradable polyesters.

  1. 1. Synthesis of degradable aliphatic polyesters: strategies to tailor the polymer microstructure

    Författare :Jenny Fagerland; Anna Finne-Wistrand; David Kaplan; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Polymer synthesis; enzymatic synthesis; degradable polyesters; peptides; scaffolds; Chemical Engineering; Kemiteknik;

    Sammanfattning : Key factors for successful tissue engineering are the synthesis and design of the scaffold materials. Aliphatic polyesters have been studied and often used as scaffold materials for tissue engineering. However, their lack of biological cues and degradation under high-temperature processing (e.g. LÄS MER

  3. 2. Towards a retro-structural design of degradable aliphatic polyester-based materials

    Författare :Veluska Arias; Ann-Christine Albertsson; Minna Kellomäki; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hydrolysis; polyesters; polylactide; hydrophobicity; crystallinity; miscibility; nanoparticles; stereocomplex; homocomposites; Kemi; Chemistry;

    Sammanfattning : The increasing amount of accumulated plastic waste has led to a continuous search for degradable materials for use in a variety of applications. This eco-friendly approach contemplates the use of degradable alternatives to the inert polymers (the main components in plastics) used today and further engineering of their degradation pathways. LÄS MER

  4. 3. Macromolecular synthesis of functional degradable aliphatic polyesters and porous scaffold design

    Författare :Sofia Målberg; Ann-Christine Albertsson; Anders Södergård; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; functional polyesters; condensation polymerization; L-lactide; ε-caprolactone; triblock copolymer; mechanical properties; porous scaffolds; tissue engineering; ring-opening polymerization; Bi III acetate; creatinine; stannous 2-ethylhexanoate; enzyme; degradation products; Polymer chemistry; Polymerkemi;

    Sammanfattning : There is an increasing demand for new materials in biomedical applications with material properties that are highly specific for each application area. The search for new materials requires the creation of materials with suitable mechanical properties, functionalities, three-dimensional structures and a controlled degradation profile. LÄS MER

  5. 4. Engineering 3D degradable pliable scaffolds for adipose tissue regeneration : Advancing cell-material interactions by understanding the influence from thermal, chemical, mechanical properties and scaffold design

    Författare :Shubham Jain; Anna Finne-Wistrand; Kamal Mustafa; Mikael Hedenqvist; Lauren Flynn; KTH; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Degradable polymers; 3D scaffolds; adipose tissue regeneration; cell-material interaction; Fiber- och polymervetenskap; Fibre and Polymer Science;

    Sammanfattning : In soft tissue defects that arise due to trauma, tumor resections and complex burns, a significant loss in adipose tissue remains a considerable challenge due to the insufficient regenerative capacity of the tissue. This thesis focuses on assessing cell-material interactions between degradable 3D polymer scaffolds with different designs and adipose tissue-derived stem cells. LÄS MER

  7. 5. Design of Functional Degradable Aliphatic Polyesters and Porous Tissue Engineering Scaffolds

    Författare :Peter Plikk; Ann-Christine Albertsson; Marek Kowalczuk; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Ring-opening polymerization; Stannous octoate; 2; 2’-azoisobutyronitrile; 1; 5-dioxepane-2-one; ε-caprolactone; L-lactide; Trimethylene carbonate; 2-methylene-1; 3-dioxe-5-pene; Copolymer; Porous scaffold; Porous tubular scaffold; Electron beam; Gamma irradiation; Polymer chemistry; Polymerkemi;

    Sammanfattning : The regeneration of damaged tissues or organs using porous scaffolds which act as temporary guides for the patient’s own cells, i.e. tissue engineering, is a means to overcome the shortcomings of current standard medical treatments. LÄS MER