Sökning: "degenerative changes"

Visar resultat 6 - 10 av 69 avhandlingar innehållade orden degenerative changes.

  1. 6. Mass spectrometry for comparative proteomics of degenerative and regenerative processes in the brain

    Författare :Carina Sihlbom; Göteborgs universitet; []
    Nyckelord :glycoproteomics; quantitative proteomics; glycoprotein; protein quantification; glycosylation; Fourier transform ion cyclotron mass spectrometry; cerebrospinal fluid; Alzheimer s disease; neurodegeneration; neuroregeneration; hippocampus; astrocytes; brain injury; 14-3-3 protein; isoform;

    Sammanfattning : Biological processes involve changes at the protein level. Proteomics aims to determine protein changes from a normal state, to measure for instance recovery or disease progression. Mass spectrometry is the most important tool for identification of proteins and determination of post-translational modifications such as glycosylation. LÄS MER

  2. 7. Measurement of outcome in lumbar spine surgery : Validity and interpretability of frequently used outcome measures in the Swespine register

    Författare :Catharina Parai; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; spine register; disc herniation; spinal stenosis; degenerative disc disorder; patient-reported outcome measure; Global Assessment; minimal important change; smallest detectable change; retest reliability; non-response to follow-up; attrition; measurement of change;

    Sammanfattning : BACKGROUND. The purpose of elective lumbar spine surgery is mainly to reduce pain and to improve physical function and quality of life. The quality and results of the interventions are monitored in the Swedish spine register, Swespine. LÄS MER

  3. 8. Cell Therapy in lntervertebral Disc Degeneration

    Författare :Papadimitriou Nicolaos; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Low back pain; Mesenchymal stromal cell; Intervertebral disc; Intervertebral disc degeneration; Degenerative disc disease; Cell therapy;

    Sammanfattning : Background: Chronic low back pain (LBP) is the leading cause of disability worldwide. Intervertebral disc degeneration (IDD) is central in the pathogenesis. The injection of bone marrow-derived mesenchymal stromal cells (BM-MSCs) into degenerate intervertebral discs (IVDs) has been proposed as an alternative therapy. LÄS MER

  4. 9. Spinal column and hip joint changes, and their correlation to back pain in young athletes - Radiological and Clinical Studies

    Författare :Wisam Witwit; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Sports Medicine;

    Sammanfattning : Background: Young athletes are at increasing risk for spinal column injuries and back pain due to excessive sporting activities, with potential development of complications like spinal canal stenosis and chronic back pain later in life. Increased knowledge is necessary in order to make the correct diagnosis and to be able to adapt the appropriate preventive measures, rehabilitation programs, and treatments accordingly. LÄS MER

  5. 10. Evolving geriatric anthropometrics- an interplay with lifestyle changes, birth cohort effects, and survival implications. : Results from the general population study, “Good Aging in Skåne,” Sweden

    Författare :Nivetha Natarajan Gavriilidou; Geriatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anthropometrics; BMI misclassification; measurement; error correction; prediction equation; surrogate; survival; lifestyle; birth cohort; Swedish elderly; assessment;

    Sammanfattning : There is a rising proportion of aging population worldwide. The high vulnerability of older adults to morbidity and mortality introduces an enormous health and economic burden to themselves and the society. The established leading cause of death among older adults is due to chronic and vascular diseases. LÄS MER