Sökning: "defekt typer"

Visar resultat 1 - 5 av 21 avhandlingar innehållade orden defekt typer.

  1. 1. Diamond-Blackfan Anemia: Erythropoiesis Lost in Translation

    Författare :Johan Flygare; Stefan Karlsson; Avdelningen för molekylärmedicin och genterapi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; extracellular fluids; Hematologi; Haematology; RNA interference; Erythropoiesis; Lentiviral vectors; Nucleolus; Diamond-Blackfan anemia; Gene therapy; extracellulära vätskor;

    Sammanfattning : Diamond-Blackfan anemia (DBA) is a congenital erythroid aplasia that usually presents as macrocytic anemia during infancy. Linkage analysis suggests that at least four genes are associated with DBA of which two have been identified so far. LÄS MER

  3. 2. Immunosuppressive Myeloid Cells in Breast Cancer and Sepsis

    Författare :Caroline Bergenfelz; Institutionen för translationell medicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES;

    Sammanfattning : Immune cells play paradoxical roles in cancer progression. On one hand, the immune system protects us against tumor development by recognizing and eliminating cancerous cells. LÄS MER

  4. 3. End-to-side nerve repair - A study in the forelimb of the rat

    Författare :Eleana Bontioti; Malmö Institutionen för kliniska vetenskaper; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Nerve regeneration; Kirurgi; traumatology; Surgery; orthopaedics; Medicin människa och djur ; Medicine human and vertebrates ; Retrograde labelling; ATF3; Collateral sprouting; ortopedi; traumatologi; Nerve injury;

    Sammanfattning : Nerve injuries have a profound impact on individuals, suffering for the patients and induce cost for society. When dealing with severe nerve injuries that create a gap between nerve segments or when the injury is at the brachial plexus level, the clinical alternatives are limited. LÄS MER

  5. 4. Aggressive lymphoma

    Författare :Mats Jerkeman; Bröstcancer-genetik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cytology; BCL6 rearr; 1q21-23; cytogenetics; histopathology; P-glycoprotein; p53; BCL2; Ki-67; immunohistochemistry; proliferation; dose intensity; health-related quality of life; International Prognostic Index; prognostic factors; aggressive lymphoma; chemotherapy; patologisk anatomi; Patologi allmän ; pathological anatomy; General pathology; cancer; onkologi; Cytologi; cancerology; oncology;

    Sammanfattning : Aggressive lymphoma is a rapidly growing tumour of lymphocyte origin, potentially curable with chemotherapy. In a trial by the Nordic Lymphoma Group, 405 patients with aggressive lymphoma were included, and randomised to receive either the standard chemotherapy regimen, CHOP, or a weekly multidrug regimen, MACOP-B. LÄS MER

  7. 5. TRIM22/Staf50 - a novel target gene of the tumor suppressor p53

    Författare :Susanna Obad; Avdelningen för hematologi och transfusionsmedicin; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Hematologi; extracellular fluids; Haematology; Medicin människa och djur ; Medicine human and vertebrates ; T lymphocyte; apoptosis; PML; differentiation; hematopoiesis; leukemia; interferon; p53; TRIM22 Staf50; extracellulära vätskor;

    Sammanfattning : The tumor suppressor gene p53 is a transcription factor that mediates cell cycle arrest, apoptosis and differentiation. p53 mediated differentiation of leukemic cells depends on the transcriptional activity of p53 but so far no obvious differentiation inducing target gene has been identified. LÄS MER