Sökning: "decidualization"

Hittade 2 avhandlingar innehållade ordet decidualization.

  1. 1. Monoamine transporters in female human reproduction

    Författare :Barbara Bottalico; Lund Obstetrik och gynekologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PMAT; VMAT2; OCT; NET; in-situ hybridization histochemistry; decidualization; human endometrium; placenta; Medicine human and vertebrates ; Monoamine transporters; preeclampsia; histamine; Medicin människa och djur ;

    Sammanfattning : The present study explored the gene and protein expression of the monoamine transporters in human endometrium throughout the menstrual cycle, in early decidua and in placentas from normal as well as preeclamptic pregnancies using in-situ hybridization, real time-PCR, immunohistochemistry and primary tissue cultures. Four distinguishable patterns were observed in the endometrium over the menstrual cycle: (1) epithelial expression of norepinephrine transporter (NET) mRNA, (2) Stromal co- expression of vesicular monoamine transporter 2 (VMAT2) and plasma membrane monoamine transporter (PMAT) mRNAs with maximal intensity in the proliferative phase; (3) increasing epithelial expression of VMAT2 mRNA with a maximum in the late secretory phase; (4) stromal expression of extra-neuronal monoamine transporter (EMT) mRNA with a peak in the early secretory phase. LÄS MER

  3. 2. Effects of insulin on the decidualization of human endometrial stromal cells : in vitro studies

    Författare :Ivika Jakson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Hyperinsulinemia is a known characteristic of obesity and polycystic ovary syndrome, two common clinical conditions associated with reproductive problems. However, the underlying mechanisms to reduced fertility are not fully elucidated, and the role of insulin in reproduction needs further investigation. LÄS MER