Sökning: "dansyl"

Hittade 3 avhandlingar innehållade ordet dansyl.

  1. 1. Sensitivity and selectivity studies in capillary electrophoresis

    Författare :Maria Petersson; Centrum för analys och syntes; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; peptides; dansyl amino acids; imaging detection; cyclodextrins; enantiomer separation; acoustic levitation; solid-phase extraction; preconcentration; capillary electrophoresis; micellar electrokinetic chromatography; drugs; Analytical chemistry; Analytisk kemi;

    Sammanfattning : Capillary electrophoresis is characterised by high separation efficiency, applicability to a wide range of compounds, small sample and solvent consumption and simple instrumentation. To improve sensitivity using on-line absorbance detectors, which are hampered by the short optical path length, sample volumes in the microlitre range were concentrated to nanolitre volumes either off-line or on-line. LÄS MER

  3. 2. Targeting Biological Systems by Organic Synthesis Methods - Cancer Cells and Proteins

    Författare :Cecilia Winander; Lars Baltzer; Stefan Sjöberg; Jörgen Carlsson; Vladimir Tolmachev; Thomas Schrader; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Organic chemistry; carborane; doxorubicin; 125I; molecular recognition; four-helix bundle; polypeptide conjugate; affinity; chitinase; acetylcholine esterase; Organisk kemi;

    Sammanfattning : This thesis describes the design and synthesis of molecules with potential roles in biomedicine, with an emphasis on molecular recognition in complex biological environments. The first chapter describes the synthesis and evaluation of compounds for use in nuclide therapy. LÄS MER

  4. 3. Lipase-Lipid Interactions Studied by Site-Directed Labeling and Biological Spectroscopy

    Författare :Eva Hedin; Karl Hult; Marek Brzozowski; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; thermomyces lanuginous lipase; site-directed labeling; lipase-lipid interactions; Biochemistry; Biokemi;

    Sammanfattning : This thesis describes the study of lipase–lipid interactions of the triglyceride lipase Thermomyces lanuginosus lipase, TLL, by use of site-directed chemical labeling and biological spectroscopy. Several single-cysteine variants of TLL were produced, and labeled with probes containing either an affinity-, a fluorescence- or a spin-label functionality. LÄS MER