Sökning: "dagnell"

Hittade 2 avhandlingar innehållade ordet dagnell.

  1. 1. Studies on neurotrophins in inflammatory pulmonary diseases

    Författare :Charlotta Dagnell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Asthma, sarcoidosis and chronic obstructive pulmonary disease (COPD) are inflammatory pulmonary diseases, all being characterized by tissue inflammation, tissue damage (airway remodeling) and loss of lung function. In order to increase possibilities to find new biomarkers, drug targets and better treatment options for the patients, further research on the underlying mechanisms driving the inflammation and airway remodeling in these diseases are required. LÄS MER

  3. 2. Redox-regulation of PTPs : mechanisms and impact on PDGFR signaling

    Författare :Markus Dagnell; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Protein tyrosine phosphatases (PTPs) are reversibly oxidized upon activation of platelet-derived growth factor receptor beta (PDGFβR). Dys-regulation of the PDGFβR signaling pathway is associated with several diseases, including cancers and cardiovascular disease, and is thus a known driver of disease progression. LÄS MER