Sökning: "cytotoxic T lymphocyte"
Visar resultat 1 - 5 av 78 avhandlingar innehållade orden cytotoxic T lymphocyte.
1. Human intestinal T lymphocytes : a comparative analysis of phenotype and function in normal and inflamed mucosa
Sammanfattning : The epithelial lining of the gut must allow immediate contact with beneficial components as nutrients and normal microflora. At the same time it runs the constant risk of attack from pathogenic microbes and noxious agents. LÄS MER
2. T-cells in COPD to help or harm? A study of T-cells in COPD patients and related aspects of T-cell function in vitro
Sammanfattning : Chronic obstructive pulmonary disease, COPD, is manifested by chronic airflow limitation due to inflammation and tissue destruction in the lungs. COPD is caused primarily by smoking and with increasing cigarette consumption in the world, the prevalence for COPD will most probably increase in the future. LÄS MER
3. Regulation of cytotoxic lymphocyte effector functions
Sammanfattning : Studies of patients with inborn errors of immunity provide an important opportunity to understand the human immune system in a natural context. The articles in this thesis are a compilation of such investigations. LÄS MER
4. The Multiple Faces of Genetically-Modified T Cells : Potential Applications in Therapy
Sammanfattning : In this PhD thesis the potential of T-cells as therapy for disease are explored. The applications of genetically modified T-cells for treatment of cancer and autoimmune disease; the functionality and optimal activation of T-cells are discussed. LÄS MER
5. Regulation of lymphocyte activation and death
Sammanfattning : T lymohocytes (T cells) and B lymphocytes (B cells) are important effector cells of the adaptive immune system. In response to infections, B cells are activated and produce antibodies against specific antigens. LÄS MER