Sökning: "cytoplasmic genome"

Visar resultat 21 - 25 av 40 avhandlingar innehållade orden cytoplasmic genome.

  1. 21. The Regulation of Human Papillomavirus Type16 Early Gene Expression

    Författare :Xiaoxu Cui; Avdelningen för medicinsk mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Human papillomavirus; splicing; hnRNP D; m6A; LCR;

    Sammanfattning : AbstractHuman papillomaviruses (HPVs) are small non enveloped viruses that contain a double-stranded circular DNA genome of approximately 8kb in size. It has been estimated that approximately 5% of all cancers are caused by HPV infection. Cervical cancer represents the majority of HPV-associated anogenital cancers worldwide. LÄS MER

  2. 22. Cyclins on the move : a time and a place for cyclin A2 and cyclin B1 in the human cell cycle

    Författare :Helena Silva Cascales; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The ultimate aim of the cell cycle is to create an identical daughter cell. Therefore, correct progression through the different phases of the cell cycle is crucial to ensure faithful cell division. LÄS MER

  3. 23. Molecular markers reflecting malignant transformation and tumor progression

    Författare :Patricia Stoltzfus; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Molecular markers; interphase fluorescence in situ hytidization; genetic diagnostic test; laminin-5 gamma2 chain; immunohistochemistry; precancerous lesions; invasiveness; breast cancer; cervical squamous cell carcinoma; tongue carcinoma; vulvar carcinoma;

    Sammanfattning : The early detection of neoplastic lesions is most critical in the successful treatment of malignant disease. This thesis investigates molecular targets for an improved detection and diagnosis of cancer by exploring the value of interphase fluorescence in situ hybridization (FISH) to detect specific chromosomal aneuploidies and gene amplifications, and laminin-5 gamma2 chain expression detected by immunohistochemistry as a marker for invasiveness. LÄS MER

  4. 24. Pathogenic mechanisms affecting mitochondrial DNA replication and transcription

    Författare :Meenakshi Singh; Göteborgs universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; mtDNA; ribonucleotides; nucleoside analogues; POLRMT;

    Sammanfattning : Mitochondria are cytoplasmic organelles fundamental to life and health. In mitochondria, energy from the food we eat is converted into adenosine triphosphate (ATP), which in turn is used as a source of chemical energy to drive a multitude of cellular reactions. LÄS MER

  5. 25. Evolution of biological systems linked to complex cell architectures in Planctomycetota

    Författare :Emil Hägglund; Siv Andersson; Damien Devos; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Planctomcyetota; Cellular complexity; Gemmataceae; Phagocytocis; Serine Threonine kinase; Anammox; Hydrazine Synthase; Hydroxylamine oxidoreductase; Heme biosynthesis; Phylogenetics; Biologi med inriktning mot molekylär evolution; Biology with specialization in Molecular Evolution;

    Sammanfattning : The eukaryotic cells have a nucleus and membrane-enclosed organelles for functions such as energy production, whereas the prokaryotic cells have a cell wall but no intracellular membrane-bound structures. Species of the Planctomycetota phylum are classified as bacteria but have diverse and complex cell architectures. LÄS MER