Sökning: "cytolytic T lymphocyte-associated antigen-4 CTLA-4"

Hittade 1 avhandling innehållade orden cytolytic T lymphocyte-associated antigen-4 CTLA-4.

1. 1. Genetic and immunological control of human myasthenia gravis

   Författare :Xiaoyan Zhao; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Myasthenia Gravis MG ; beta2-adrenergic receptor beta2-AR ; CCR2; CCR5; cytolytic T lymphocyte-associated antigen-4 CTLA-4 ; OX40;

   Sammanfattning : Myasthenia gravis (MG) is a classical autoimmune disease characterized by muscle weakness due to an immune attack against the nicotinic acetylcholine receptor (AChR) on the post-synaptic membrane of the neuromuscular junction. Because of the involvement of multiple factors in the disease, the overall aims of this thesis were to uncover the regulation of candidate genes and the possible cellular mechanisms involved in the immuno-regulation of human MG. LÄS MER