Sökning: "cytokine release syndrome"

Visar resultat 1 - 5 av 14 avhandlingar innehållade orden cytokine release syndrome.

  1. 1. Antibody- and Peptide-based Immunotherapies : Proof-of-concept and safety considerations

    Författare :Erika Fletcher; Sara Mangsbo; Vivianne Malmström; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Immune complex; conjugat; vaccine; CD40; whole blood; cytokine release syndrome; Immunologi; Immunology;

    Sammanfattning : The aim of cancer immunotherapy is to eradicate tumours by inducing a tumour-specific immune response. This thesis focuses on how antibodies and peptides can improve antigen presentation and the subsequent tumour-specific T cell response. Tumour recognition by the immune system can be promoted through delivery of antigen in the form of a vaccine. LÄS MER

  3. 2. Potential role of anti-cytokine autoantibodies in the regulation of cytokine responses in infections and autoimmune diseases

    Författare :Rihab Abdel Magid Awad El Karim; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :cytokines; autoantibodies; MS; AM; ST; MGUS; GBS; lower respiratory tract infection; mAbs;

    Sammanfattning : Anti-cytokine autoantibodies are serum proteins that bind cytokines and specifically interfere with measurements and biological activities of the corresponding cytokines. Plasma, sera, and CSF were obtained from patients with multiple sclerosis (MS), aseptic meningitis (AM), stroke (ST), and polyneuropathy, Guillain Barré Syndrome (GBS). LÄS MER

  4. 3. Acute cytokine responses to inhaled swine confinement building dust

    Författare :Zhiping Wang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Inhalation of swine house dust (swine dust) may cause an acute inflammatory reaction Organic Dust Toxic Syndrome (ODTS). The reaction does not require sensitisation and is associated with airway inflammation, general symptoms, and slight spirometric changes. The agents and causing this reaction are not known. LÄS MER

  5. 4. Studies on T cells and cytokines in Guillain-Barré syndrome and experimental allergic neuritis

    Författare :Charlotte Rüdhmer-Dahle; Jan Ernerudh; Jan Hillert; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : Guillain-Barrésyndrome (GBS) is an inflammatory disease of peripheral nerves, characterised by muscle weakness. The nerves are attacked and destroyed by the immune system. The symptoms usually progress over a few weeks and many patients become severely disabled. LÄS MER

  7. 5. Activation of human dendritic cells : role of the allergenic yeast Malassezia and NK cells

    Författare :Eva Buentke; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Antigen-presenting cells; atopic eczema dermatitis syndrome; cytokines; dendritic cells; Malassezia; NK cells; yeast;

    Sammanfattning : Immature bone marrow derived dendritic cells (DCs) patrol the periphery of our body, where they encounter and take up foreign antigens. Once activated, DCs migrate to regional lymph nodes to present peptides derived from these antigens to naive T cells, and elicit different T helper (Th) cell responses. LÄS MER