Sökning: "cystic fibrosis"

Visar resultat 11 - 15 av 89 avhandlingar innehållade orden cystic fibrosis.

  1. 11. Functional Aspects of Epithelia in Cystic Fibrosis and Asthma

    Författare :Zhanna Servetnyk; Godfried Roomans; Michael Wilschansky; Uppsala universitet; []
    Nyckelord :Cell biology; cystic fibrosis; CFTR; chloride transport; airway epithelium; sweat gland; asthma; corticosteroids; montelukast; Cellbiologi;

    Sammanfattning : The cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP activated chloride channel in the apical membrane of epithelial cells, is defective in patients with cystic fibrosis (CF). Research efforts are focused on chloride channel function in order to find a cure for the disease. LÄS MER

  3. 12. Cell responses in infected and cystic fibrosis respiratory epithelium

    Författare :Rashida Hussain; Godfried M . Roomans; Maria Björkqvist; Ferenc Karpati; Hans Kollberg; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; airway epithelial cells; cystic fibrosis; bacterial infection; CFTR; ENaC; chloride transport; intracellular calcium; P. aeruginosa internalization; Biomedicin; Biomedicine;

    Sammanfattning : Respiratory Epithelium. Örebro Studies in Medicine 99. Cystic fibrosis (CF) is caused by a mutation in a cAMP-activated chloride (Cl-) channel (CFTR). Mortality and morbidity in CF is mainly due to the deregulated responses of the airway epithelial cells. LÄS MER

  4. 13. Studies on Airway Surface Liquid in Connection with Cystic Fibrosis

    Författare :Inna Kozlova; Godfried Roomans; Anca Dragomir; Marieann Högman; Isabelle Sermet-Gaudelus; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cystic fibrosis; CFTR; airway surface liquid; ion content; anesthesia; mist tent therapy; Pseudomonas aeruginosa infection; Cell biology; Cellbiologi;

    Sammanfattning : Cystic fibrosis (CF) is one of the most common fatal inherited diseases, most prevalent among Caucasians. CF is caused by a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), which helps to create sweat, digestive juices, and airway surface liquid (ASL). LÄS MER

  5. 14. Approaches to Pharmacological Treatment and Gene Therapy of Cystic Fibrosis

    Författare :Anca Dragomir; Godfried M. Roomans; Robert Dormer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomy; airway epithelium; colchicine; cystic fibrosis; chloride transport; genotype; heparin; phenotype; transfection; X-ray microanalysis; Anatomi; Anatomy; Anatomi;

    Sammanfattning : Cystic fibrosis (CF) is the most common lethal genetic disease in the white population. It is due to mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), a protein that functions mainly as a cAMP-activated chloride channel. LÄS MER

  7. 15. Ion transport in exocrine glands with reference to cystic fibrosis

    Författare :Ailing Zhang; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cell biology; ion transport; cystic fibrosis; submandibular gland; airway submucosal gland; X-ray microanalysis; cytosolic Ca2 concentration; immunocytochemistry; Cellbiologi; Cell biology; Cellbiologi; Human Anatomy; anatomi;

    Sammanfattning : Aspects of ion transport in rat submandibular gland acinar cells at the subcellular level, and the regulation of chloride secretion and calcium mobilization in cultured pig tracheal gland acinar cells were studied with reference to the disease cystic fibrosis.In adult rat submandibular gland acinar cells, both cholinergic and α-adrenergic stimulation induced efflux of K+ and of C1-, but the response was generally less with α-adrenergic stimulation. LÄS MER