Sökning: "cystic fibrosis transmembrane conductance regulator CFTR"

Visar resultat 6 - 10 av 17 avhandlingar innehållade orden cystic fibrosis transmembrane conductance regulator CFTR.

  1. 6. Functional Aspects of Epithelia in Cystic Fibrosis and Asthma

    Författare :Zhanna Servetnyk; Godfried Roomans; Michael Wilschansky; Uppsala universitet; []
    Nyckelord :Cell biology; cystic fibrosis; CFTR; chloride transport; airway epithelium; sweat gland; asthma; corticosteroids; montelukast; Cellbiologi;

    Sammanfattning : The cystic fibrosis transmembrane conductance regulator (CFTR), a cAMP activated chloride channel in the apical membrane of epithelial cells, is defective in patients with cystic fibrosis (CF). Research efforts are focused on chloride channel function in order to find a cure for the disease. LÄS MER

  3. 7. Clinical and genetical studies in cystic fibrosis and pseudohypoaldosteronism

    Författare :Charlotta Schaedel; Lund Pediatrik; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; pseudohypoaldosteronism type 1; cystic fibrosis transmembrane conductance regulator CFTR ; Cystic fibrosis; pulmonary disorder; Pediatrics; epithelial sodium channel ENaC; Pediatri;

    Sammanfattning : Cystic fibrosis (CF) is the most common severe autosomal recessive disorder among Caucasians and is caused by mutations of the chloride channel, CFTR (cystic fibrosis transmembrane conductance regulator) gene. Despite a markedly improved median survival many CF patients still die at a young age. LÄS MER

  4. 8. Studies on Airway Surface Liquid in Connection with Cystic Fibrosis

    Författare :Inna Kozlova; Godfried Roomans; Anca Dragomir; Marieann Högman; Isabelle Sermet-Gaudelus; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; cystic fibrosis; CFTR; airway surface liquid; ion content; anesthesia; mist tent therapy; Pseudomonas aeruginosa infection; Cell biology; Cellbiologi;

    Sammanfattning : Cystic fibrosis (CF) is one of the most common fatal inherited diseases, most prevalent among Caucasians. CF is caused by a mutation in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), which helps to create sweat, digestive juices, and airway surface liquid (ASL). LÄS MER

  5. 9. Cystic fibrosis in adults. Diagnostic, epidemiologic and quality-of-life aspects

    Författare :Marita Gilljam; Göteborgs universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cystic fibrosis; Cystic fibrosis transmembrane conductance regulator; Pregnancy; Male infertility; Bronchoalveolar lavage; Quality of life; Questionnaire;

    Sammanfattning : Background: Cystic fibrosis (CF) is a severe hereditary disease. The type of mutation in the Cystic Fibrosis Transmembrane conductance Regulator (CFTR) gene will determine the degree of CFTR chloride channel malfunction. LÄS MER

  7. 10. Approaches to Pharmacological Treatment and Gene Therapy of Cystic Fibrosis

    Författare :Anca Dragomir; Godfried M. Roomans; Robert Dormer; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Anatomy; airway epithelium; colchicine; cystic fibrosis; chloride transport; genotype; heparin; phenotype; transfection; X-ray microanalysis; Anatomi; Anatomy; Anatomi;

    Sammanfattning : Cystic fibrosis (CF) is the most common lethal genetic disease in the white population. It is due to mutations in the gene coding for the cystic fibrosis transmembrane conductance regulator (CFTR), a protein that functions mainly as a cAMP-activated chloride channel. LÄS MER