Sökning: "cyclothiazide"

Hittade 3 avhandlingar innehållade ordet cyclothiazide.

1. 1. Modulation of AMPA glutamate receptor functions in primary neuronal cultures

   Författare :Gvido Cebers; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :glutamate; AMPA; cerebellar granule cells; cortical cells; cyclothiazide; AP-1; transcription factors; receptor desensitization; Ca2 ; neurotoxicity; 45Ca2 uptake; apoptosis; ischemia; muscarinic; carbachol;

   Sammanfattning : Primary neuronal cultures were used to investigate the properties of AMPA receptors and functional consequences of their activation, as well as AMPA receptor desensitization and possibilities for its modulation. We established the presence and spontaneous functional activity of AMPA receptors in cerebellar granule and cortical cell cultures. LÄS MER

3. 2. Synaptic plasticity in local networks of neocortical layer 2/3

   Författare :Misha Zilberter; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :Neocortical microcircuit; layer 2 3; pyramidal cell; spike timing- dependent plasticity; LTP; LTD; FSN interneuron; retrograde signalling; SAT2;

   Sammanfattning : The neocortex is a hierarchal organ in which information processing takes on place on many levels, from subcellular signalling all the way to neural networks. Neocortical local neuronal networks (microcircuits), composed of interconnected neurons, form elementary information processing units within the cortex. LÄS MER

4. 3. Chemical and stimulus-induced NMDA-dependent plasticity and the possible involved mechanisms

   Författare :Rui Li; Göteborgs universitet; []
   Nyckelord :synaptic plasticity; hippocampus; LTP; LTD; AMPA; NMDA; NR2A; NR2B;

   Sammanfattning : Long-term potentiation (LTP) and long-term depression (LTD) are considered as the most important forms of synaptic plasticity involved in learning and memory. The traditional way to induce LTP and LTD is by electric stimulation leading to activation of NMDA-R. LÄS MER