Sökning: "cyclization"
Visar resultat 6 - 10 av 41 avhandlingar innehållade ordet cyclization.
6. Transition-Metal Catalyzed Synthesis of Small- and Medium-Sized Rings Applications toward oxazole synthesis, cycloheptadienes, and natural products
Sammanfattning : This thesis deals with the development of novel methodologies for the synthesis of hetero- and carbocycles enabled by transition metal catalysis. The second chapter of the thesis describes a gold-catalyzed three-component reaction to form a variety of substituted oxazoles from readily available N-benzylimines, terminal alkynes, and acyl chlorides. LÄS MER
7. Metal‐Free Arylations of Oxygen and Nitrogen Nucleophiles : Applications of Diaryliodonium Salts
Sammanfattning : This thesis concerns development of new methods for metal‐free arylations in organic synthesis. The protocols discussed in the thesis are based on a class of hypervalent iodine compounds called diaryliodonium salts. These reagents are known to transfer aryl moieties to suitable nucleophiles. LÄS MER
8. Construction of Five-Membered Heterocycles via Radical Cyclization
Sammanfattning : .... LÄS MER
9. Development of Peptide Binders : Applied to Human CRP, Carbonic Anhydrase (II, IX) and Lysine Demethylase 1
Sammanfattning : In this thesis, a polypeptide binder concept is illustrated. By conjugation to a set of sixteen polypeptides, a small binding molecule can evolve into a polypeptide binder with increased affinity and selectivity. LÄS MER
10. Carbon-Carbon Bond Formation via Radical Cyclization and Transition Metal Catalysis
Sammanfattning : Free radical cyclization methodology has been used extensively in synthesis for manipulation of complex molecules such as alkaloids, terpenes, carbohydrates, peptides and nucleic acids. The methodology has emerged as a result of work by physical organic chemists who determined rate constants for the most common radical reactions used in organic synthesis. LÄS MER