Sökning: "cyclic polypeptides"

Hittade 2 avhandlingar innehållade orden cyclic polypeptides.

1. 1. From Macromolecular Design to Supramolecular Self-assembly

   Författare :Lidija Glavas; Ann-Christine Albertsson; Karin Odelius; Matthew Becker; KTH; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Self-assembly; micelles; core crystallinity; cyclic polypeptides; electroactivity; redox-responsiveness; triggered dissociation; loading; release; N-carboxyanhydride polymerization; polyesters; poly ε-decalactone ; Självorganisation; miceller; kärnkristallinitet; cykliska polypeptider; elektroaktivitet; tidsberoende dissociation; inkapsling; frisläppning; N-karboxyanhydrid polymerisation; polyestrar; poly ε-dekalakton ; Fiber- och polymervetenskap; Fibre and Polymer Science;

   Sammanfattning : Advancements in drug delivery have enabled a wider array of prevention, control and treatment of diseases such as cancer. Drug delivery systems have the possibility of encapsulating drugs with low solubility, delivering them to specific locations in the body as well as obtaining a controlled and sustained drug release. LÄS MER

3. 2. Development of Peptide Binders : Applied to Human CRP, Carbonic Anhydrase (II, IX) and Lysine Demethylase 1

   Författare :Jie Yang; Jan Kihlberg; Morten Grötli; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; polypeptide conjugates; molecular recognition; peptide cyclization; protein targets;

   Sammanfattning : In this thesis, a polypeptide binder concept is illustrated. By conjugation to a set of sixteen polypeptides, a small binding molecule can evolve into a polypeptide binder with increased affinity and selectivity. LÄS MER