Sökning: "cyanohydrin"

Visar resultat 1 - 5 av 9 avhandlingar innehållade ordet cyanohydrin.

  1. 1. New Methods for Chiral Cyanohydrin Synthesis

    Författare :Erica Wingstrand; Christina Moberg; Benjamin List; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; acyl cyanides; asymmetric synthesis; biocatalysis; cyanide; cyanohydrins; dual activation; enzymes; high-throughput screening; Lewis acid; Lewis base; metal catalysis; minor enantiomer recycling; salen; titanium; Chemistry; Kemi;

    Sammanfattning : This thesis deals with method development in asymmetric catalysis and specifically syntheses of enantioenriched O-functionalized cyanohydrins. The first part describes the development of a method for the synthesis of O‑alkoxycarbonylated and O-acylated cyanohydrins. LÄS MER

  3. 2. Cassava processing, consumption and dietary cyanide exposure

    Författare :Adeyinka Onabolu; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cassava; gari; linamarin; cyanohydrin; cyanogens; cyanide.;

    Sammanfattning : Cassava is a major component of the diet of more than half a billion people in the tropics. Cassava is an important crop in the farming system in the tropics because it can be intercropped with many other crops, and yields well in poor soils. LÄS MER

  4. 3. Enzyme selectivity as a tool in analytical chemistry

    Författare :Anders Hamberg; Karl Hult; Harry Brumer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; substrate specificity; competing substrates; enantiomeric excess analysis; library screening; ladder sequencing; carboxypeptidase Y; 2-pyridylmethylamine; MALDI; Candia antarctica lipase B; pig liver esterase; horse liver alcohol dehydrogenase; acylated cyanohydrins; Biochemistry; Biokemi;

    Sammanfattning : Enzymes are useful tools as specific analytical reagents. Two different analysis methods were developed for use in the separate fields of protein science and organic synthesis. Both methods rely on the substrate specificity of enzymes. Enzyme catalysis and substrate specificity is described and put in context with each of the two developed methods. LÄS MER

  5. 4. Development and Studies of the Processes Involved in Minor Enantiomer Recycling

    Författare :Anna Laurell Nash; Christina Moberg; Karl Anker Jørgensen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; asymmetric catalysis; biocatalysis; cyanohydrins; dual activation; Lewis acid; Lewis base; minor enantiomer recycling; recycling; titanium; Kemi; Chemistry;

    Sammanfattning : This thesis describes the development and rationalization of processes involved in a new methodology developed in our group, minor enantiomer recycling.The first part of the thesis addresses mechanistic studies of one of the reactions involved in minor enantiomer recycling, dual Lewis acid-Lewis base catalyzed acetylcyanation of aldehydes. LÄS MER

  7. 5. Serine Hydrolase Selectivity : Kinetics and applications in organic and analytical chemistry

    Författare :Anders Hamberg; Karl Hult; Dick Janssen; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Candida antarctica lipase B; monoacylation of diols; kinetic resolution; thermodynamics in enzyme catalysis; enzyme engineering; Biochemistry; Biokemi;

    Sammanfattning : The substrate selectivities for different serine hydrolases were utilized in various applications, presented in papers I-VI. The articles are discussed in the thesis in view of the kinetics of the enzyme catalysis involved. LÄS MER