Sökning: "cxcr2"

Visar resultat 1 - 5 av 13 avhandlingar innehållade ordet cxcr2.

  1. 1. Epidermal Melanocyte Response to Radiotherapy

    Författare :Per Fessé; Henrik Lindman; Ingela Turesson; Johan Ahlgren; Jan Nyman; Catharine West; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Melanocytes; fractionated radiotherapy; ΔNp63; MITF; PAX3; SOX10; p53; p21; BMI1; pRb; CXCR2; DNA-DSB; 53BP1; CXCR2;

    Sammanfattning : Cutaneous interfollicular melanocytes protect the skin from UV-radiation (UVR), and their response to UVR is well established. To date, the response activated in melanocytes by repeated genotoxic insults from radiotherapy (RT) has not been explored. LÄS MER

  3. 2. Mechanisms of Escherichia coli induced transepithelial neutrophil migration

    Författare :Gabriela Godaly; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Microbiology; UTI; mucosa; cytokine receptors; inflammation; neutrophils; chemotaxis; bacteriology; virology; mycology; Mikrobiologi; bakteriologi; virologi; mykologi;

    Sammanfattning : Mucosal infections trigger an inflammatory response that includes the secretion of cytokines and the recruitment of neutrophils to the infected site. This thesis describes studies examining the molecular mechanisms of neutrophil migration to sites of mucosal bacterial infection. Escherichia coli (E. LÄS MER

  4. 3. Fatal attraction : NK cell migration toward and activity in solid tumors

    Författare :Veronika Kremer; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Natural killer (NK) cells play a key role in tumor immunosurveillance due to their ability to induce apoptosis of tumor cells and produce pro-inflammatory cytokines, without prior immune sensitization. In particular, NK cells demonstrate potent anti-tumor immune responses against metastases and hematological malignancies. LÄS MER

  5. 4. The effect of beta2-adrenoceptor agonists and steroids on induced airway inflammation and bronchial responsiveness

    Författare :Karin Strandberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Acute exposure of healthy subjects in a swine barn induces an intense airway inflammation and increased bronchial responsiveness. Dust collected in swine houses is a potent stimulus for release of pro-inflammatory cytokines from cells in vitro. LÄS MER

  7. 5. Inflammation and cell migration in chronic obstructive pulmonary disease (COPD)

    Författare :Kristin Blidberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Chronic obstructive pulmonary disease (COPD), the fourth most common cause of death worldwide, is characterised by chronic airflow obstruction and chronic inflammation which affects large and, especially, small airways. There is an accumulation of inflammatory cells in the airways in COPD, in particular neutrophils, macrophages and CD8+ T-cells. LÄS MER