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1. 1. On Phase Behaviours in Lipid/Polymer/Solvent/Water Systems and their Application for Formation of Lipid/Polymer Composite Particles

   Författare :Anna Imberg; Per Hansson; Krister Thuresson; Uppsala universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; Biodegradable; CLSM; Composite Particles; Controlled Release; Cubic Phases; Drug Delivery; Flory-Huggins Theory; FT-PGSE-NMR; IPMS; Liquid Phase; Lipid Domains; Liquid Handler; Microspheres; Microstructure; Phase Behaviour; Phase Separation; Polymer Matrix; SAXS; Segregation; Sponge Phase; Swelling; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; fysikalisk och oorganisk farmaceutisk kemi; Physical and Inorganic Pharmaceutical Chemistry;

   Sammanfattning : A new kind of lipid/polymer composite particle, consisting of a biodegradable polymer matrix with well-defined lipid domains, has been created. The lipid used is the water-swelling lipid monoolein (MO), which forms a reversed bicontinuous cubic diamond structure in aqueous solutions. LÄS MER

3. 2. Protein Crystallization in Lipidic Sponge and Cubic Phases

   Författare :Pia Jeanette Hindrichsen; Chalmers tekniska högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; cubic phase; protein crystallization; phytantriol; small angle x-ray scattering; monoolein; L3 phase;

   Sammanfattning : .... LÄS MER

4. 3. On the crystallization of membrane proteins in lipidic sponge and cubic phases

   Författare :Pia Jeanette Hindrichsen; Chalmers tekniska högskola; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; monoolein MO ; selachyl alcohol; cubic phase; sponge phase; small angle X-ray scattering; protein crystallization; phytantriol PT ;

   Sammanfattning : Membrane proteins are involved in many important biological processes and in order to understand their mechanism, their three-dimensional structures need to be elucidated to high resolution by for example X-ray crystallography. However, there is only limited structural knowledge for membrane proteins which is partly explained by the difficulties in obtaining well-diffracting crystals. LÄS MER

5. 4. Lipidic Cubic Phase Microcrystallization and its Application in Serial Crystallography

   Författare :Rebecka Andersson; Göteborgs universitet; []
   Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Structural biology; Lipidic Cubic Phase; Cytochrome c oxidase; Serial Crystallography;

   Sammanfattning : Every living organism contain a cell membrane which is an important cell structure with a vast variety of different functions such as cell signaling, transportation and energy production. One of the most important functions is to produce energy for the cell to thrive. LÄS MER

7. 5. Lipid bilayers versus monolayers- Sponge phases and skin lipid domains

   Författare :Katarina Ekelund; Livsmedelsteknik; []
   Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; fatty acids; Langmuir-Blodgett films; AFM; domains; stratum corneum; bilayer curvature; lipids; glycerol monooleate; phase behaviour; sponge phase; L3 phase; Livsmedelsteknik; cholesterol; Food and drink technology;

   Sammanfattning : The L3, or sponge, phase is a thermodynamically stable isotropic liquid consisting of a surfactant membrane in aqueous solution. A solvent induced L3 phase is shown in systems of solvent, monoolein and water. LÄS MER