Sökning: "cryogenic target"

Visar resultat 1 - 5 av 9 avhandlingar innehållade orden cryogenic target.

  1. 1. Development and Applications of Tracking of Pellet Streams

    Författare :Andrzej Pyszniak; Tord Johansson; Markus Büscher; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; PANDA; cryogenic target; pellet; pellet target; pellet tracking; Fysik med inriktning mot kärnfysik; Physics with specialization in Nuclear Physics;

    Sammanfattning : The development of a system for optical tracking of frozen hydrogen microsphere targets (pellets) was done. It is intended for the upcoming hadron physics experiment PANDA at FAIR, Darmstadt, Germany. LÄS MER

  3. 2. Structural studies of drug targets and a drug metabolizing enzyme

    Författare :Daniela Cederfelt; U. Helena Danielson; Doreen Dobritzsch; Inari Kursula; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Biochemistry; Biophysics; Protein structure; X-ray crystallography; Cryogenic electron microscopy; Enzymology; Drug discovery; Pyrimidine degradation; Biokemi; Biochemistry;

    Sammanfattning : The work presented in this thesis describes how structural information about a protein can be acquired, and how it can be used to answer scientific questions about proteins’ function, their dynamic behaviour and their interactions with other proteins or ligands.The catalytic function of the pyrimidine-degrading, drug metabolizing enzyme β-ureidopropionase (βUP) is dependent on the shift between oligomeric states. LÄS MER

  4. 3. Life of a Photon in X-ray Spectroscopy

    Författare :Jens Uhlig; NanoLund: Centre for Nanoscience; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis summarizes the experimental work in which an ultrafastX-ray laser plasma source was combined with variousscalable direct detection schemes to test a novel approach forlab-based time-resolved X-ray absorption spectroscopy. A laserplasma source based on a water jet target was built and commissioned. LÄS MER

  5. 4. Compact Soft X-Ray Microscopy : Sources, Optics and Instrumentation

    Författare :Per Takman; Hans Hertz; Janos Kirz; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; soft x-ray microscopy; water window; compact; laser plasma; liquid jet; zone plate optics; Physics; Fysik;

    Sammanfattning : This thesis describes the development of a sub-60-nm full-period resolution compact soft x-ray microscope operating in the water-window region (2.3-4.4 nm). Soft x-ray water-window microscopy is a powerful technique for high-resolution imaging of organic materials exploiting the natural contrast mechanism between carbon and oxygen, cf. LÄS MER

  7. 5. Cryo-EM and Computational Biology of Macromolecular Complexes

    Författare :Andrew Emmerich; Suparna Sanyal; Erik Lindahl; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Biology with specialization in Molecular Biology; Biologi med inriktning mot molekylärbiologi;

    Sammanfattning : The ribosome is a large, ancient multicomponent macromolecular complex which is highly amenable to study by cryogenic electron microscopy (cryo-EM) and computation biology methods. This thesis delves into the structure of both prokaryotic and eukaryotic ribosomes in the context of determining a solution to emerging antimicrobial resistance. LÄS MER