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  1. 1. Swelling and Microstructure of Nanoplatelet Systems

    Författare :Axel Thuresson; Beräkningskemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Nanoplatelets; Model clay system; Coarse grained models; Statistical mechanics; MC simulations; MD simulations; SAXS; Cryo-TEM; Laponite; Montmorillonite; Swelling; Tactoid;

    Sammanfattning : Many clay minerals consist of charged nanoplatelets that swell in an aqueous solution. The swelling and the microstructure depend on the type of clay mineral but are also dependent on, for example, the ionic composition and the temperature of the solution. LÄS MER

  3. 2. Sterically stabilised liposomes and related lipid aggregates : Fundamental studies on aggragate structure and stability

    Författare :Markus Johnsson; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physics; liposome; steric stabilisation; colloidal stability; cryo-TEM; drug delivery; Fysik; Physics; Fysik; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : Various aspects of and approaches towards the steric stabilisation of liposomes have been investigated, mainly by use of fluorescence techniques and cryo-transmission electron microscopy (cryo-TEM). It is shown that PEG(2000)-lipids can be incorporated in the liposome membrane up to a critical concentration of 8-10 mol% without any observable structural perturbations. LÄS MER

  4. 3. Milk Membrane Lipids - Dispersions, Emulsions and Interactions with Proteins

    Författare :Rianne Waninge; Livsmedelsteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Food and drink technology; Model milk membrane lipids; Emulsions; Vesicles; Cryo-TEM; Milk fat globule membrane; MFGM; Livsmedelsteknik;

    Sammanfattning : Milk is a dilute aqueous dispersion with a complex mixture of proteins, fat, carbohydrates, vitamins and minerals. Milk membrane lipids are a part of the milk fat globule membrane (MFGM), which covers the fat globules. During dairy processing membrane material is released and surface structure features are altered. LÄS MER

  5. 4. Protein-Surfactant Interactions Phase Behaviour and Phase Structure

    Författare :Anna Karin Morén; Fysikalisk kemi; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Phase equilibria; Protein-surfactant interactions; Gel; Precipitate; Solution; Lysozyme; b-lactoglobulin; Ovalbumin; Bovine serum albumin; Dodecyltrimethylammonium chloride; Sodium alkylsulphates; NMR; Cryo-TEM; Physical chemistry; Fysikalisk kemi;

    Sammanfattning : Protein-surfactant interactions in water are investigated by following the phase equilibria for protein-surfactant pairs whose constituents carry both opposite and the same sign of charge. The concentration ranges studied are: 0-20 wt% protein, 0-20 wt% surfactant, and 80-100 wt% water. LÄS MER

  7. 5. Liposomes for Drug Delivery : from Physico-chemical Studies to Applications

    Författare :Nill Bergstrand; Katarina Edwards; Felix M Goni; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Physical chemistry; liposome; steric stabilisation; BNCT; cryo-TEM; EGF; targeting; stability; permeability; pH-sensitive liposomes; triggered release; Fysikalisk kemi; Physical chemistry; Fysikalisk kemi; Physical Chemistry; fysikalisk kemi;

    Sammanfattning : Physico-chemical characterisation of structure and stability of liposomes intended for drug delivery is the central issue in this thesis. In addition, targeted liposomes to be used in boron neutron capture therapy (BNCT) were developed.Lysolipids and fatty acids are products formed upon hydrolysis of PC-lipids. LÄS MER