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Visar resultat 1 - 5 av 8 avhandlingar som matchar ovanstående sökkriterier.

  1. 1. Photocontact Allergy to Ketoprofen and Simultaneous Contact Allergies

    Författare :Victoria Marmgren; Yrkes- och miljödermatologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; ketoprofen; photoallergic contact dermatitis; cross-reactions; photoallergic; photopatch testing; Fragrance; patch testing; simultaneous reactions; occlusion;

    Sammanfattning : Ketoprofen is a non-steroidal anti-inflammatory drug with analgesic, antipyretic, and anti-inflammatory properties. It is available in both oral and topical formulations. Photocontact allergy to topically applied ketoprofen has been the most frequent side effect of the formulation, and is fairly well studied. LÄS MER

  3. 2. Autoantigenic properties of the U1-70K protein

    Författare :Elisabet Welin Henriksson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :U1-70K protein; ribonucleoproteins; autoantigens; autoantibodies; epitopemapping; connective tissue disease; species specificity; cross reactions; amino acidsequence; recombinant proteins; mutagenesis;

    Sammanfattning : Patients with the autoimmune diseases systemic lupus erythematosus and mixed connective tissue disease produce autoantibodies directed towards specific groups of cellular constituents in their own body. Two of the targeted antigens are denoted Sm and RNP, and consist of distinct collections of splicing associated RNA-protein complexes. LÄS MER

  4. 3. Glutathione transferases : markers for renal disease

    Författare :Anders Sundberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Glutathione transferases (GST) alpha and pi were purified to homogeneity and used to develop immunochemical methods for analysis of the amount of these proteins in human urine. The methods were employed for diagnosis of renal dysfunctions caused by drugs and industrial chemicals. LÄS MER

  5. 4. Reactive arthritis : The human antibody responce elicited by Yersinia enterocolitica and Clamydia trachomatis

    Författare :Anders Grönberg; Östergötlands Läns Landsting; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : A central issue in the pathogenesis of reactive arthritis (ReA) is whether or not individuals developing arthritis have an aberrant immune response to individual antigens of potential triggering microorganisms. Although evidence exists that Yersinia and Chlamydia are two agents that precipitate ReA it has not been shown that these pathogens share common antigens. LÄS MER

  7. 5. Functional Role of Immune Complexes in Rheumatic and Parasitic Diseases

    Författare :Erik Åhlin; Johan Rönnelid; Karlis Pauksens; Bo Nilsson; Joachim Lundahl; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Clinical immunology; Klinisk immunologi; Medical Science; Medicinsk vetenskap;

    Sammanfattning : Immune complexes (IC) have key pathological roles in both autoimmune and infectious diseases. In this thesis functional mechanisms behind IC-driven inflammation in rheumatic diseases and tropical infections have been studied, with special focus on the contribution of autoantibodies and cytokine-inducing properties of IC. LÄS MER