Sökning: "critical illness myopathy"

Visar resultat 1 - 5 av 6 avhandlingar innehållade orden critical illness myopathy.

1. 1. Critical illness myopathy : mechanisms and pharmacological interventions

   Författare :Hazem Akkad; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : The human body typically contains over 600 skeletal muscles that make up about 40% of total body weight. These muscles work together to perform functions such as locomotion, breathing, mastication, heat regulation and speech. LÄS MER

3. 2. Critical illness myopathy : understanding different effects on muscle fibre function

   Författare :Hannah Ogilvie; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Skeletal muscle is an essential component of the human body, being one of the most dynamic and plastic tissues. As such it can be altered by numerous confounding factors. LÄS MER

4. 3. Critical illness myopathy : effects of specific intervention strategies and molecular mechanisms

   Författare :Rebeca Corpeño Kalamgi; Karolinska Institutet; Karolinska Institutet; []
   Nyckelord :;

   Sammanfattning : Skeletal muscles are a tissue with remarkable adaptability and are essential in the body in many aspects. The homeostasis of the muscles is vital for the maintenance of the body, thus muscle damage is associated with several diseases and leads to a poor quality of life. LÄS MER

5. 4. Muscle Wasting in a Rat ICU Model : Underlying Mechanisms and Specific Intervention Strategies

   Författare :Heba Salah; Lars Larsson; Sven Tågerud; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; BGP-15; critical illness myopathy; janus kinase; intensive care unit; mechanical loading; muscle wasting; signal Transducer and Activator of Transcription; ventilator-induced diaphragm dysfunction; Anestesiologi och intensivvård; Anaesthesiology and Intensive Care; Clinical Neurophysiology; Klinisk neurofysiologi;

   Sammanfattning : Critical care has undergone several developments in the recent years leading to improved survival. However, acquired muscle weakness in the intensive care unit (ICU) is an important complication that affects severely ill patients and can prolong their ICU stay. LÄS MER

7. 5. Intensive Care Unit Muscle Wasting : Skeletal Muscle Phenotype and Underlying Molecular Mechanisms

   Författare :Sudhakar Reddy Aare; Larsson Lars; Rooyackers Olav; Uppsala universitet; []
   Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; acute quadriplegic myopathy; gene expression; myosin; heat shock proteins; mechanical ventilation; myostatin; sepsis; corticosteroids; diaphragm; Clinical Neurophysiology; Klinisk neurofysiologi;

   Sammanfattning : Acute quadriplegic myopathy (AQM), or critical illness myopathy, is a common debilitating acquired disorder in critically ill intensive care unit (ICU) patients characterized by generalized muscle wasting and weakness of limb and trunk muscles. A preferential loss of the thick filament protein myosin is considered pathognomonic of this disorder, but the myosin loss is observed relatively late during the disease progression. LÄS MER