Sökning: "crimean congo"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden crimean congo.

  1. 1. Pathogenesis of an emerging pathogen : Crimean-Congo hemorrhagic fever virus

    Författare :Anne-Marie Connolly-Andersen; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Epithelial cells represent the first barrier to viral infection and the site of viral entry and release is often intimately connected with viral spread and pathogenesis. The plasma membrane of epithelial cells is polarized into an apical and basolateral domain separated by tight junctions (TJs). LÄS MER

  2. 2. Virus-host interactions : entry and replication of Crimean-Congo hemorrhagic fever virus

    Författare :Cecilia Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Crimean-Congo hemorrhagic fever (CCHF) is a severe acute human disease with potential lethal outcome caused by a virus, Crimean-Congo hemorrhagic fever virus (CCHFV). Not much is known regarding how CCHFV infects cells, replicates and why it cause vascular dysfunction. LÄS MER

  3. 3. Crimean-Congo hemorragic fever virus : studies on molecular pathogenesis and host-cell interactions

    Författare :Helen Karlberg; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Crimean-Congo haemorrhagic fever (CCHF) disease in humans shows a spectrum of severity, from mild to acute. The pathogenesis of this and other viral haemorrhagic fevers (VHF) is associated with alteration of vascular barrier function and haemorrhage, but the specific underlying mechanism is unknown. LÄS MER

  4. 4. Crimean-Congo hemorrhagic fever virus : interferon-induced antiviral mechanisms and immune evasion strategies

    Författare :Ida Andersson; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : The Bunyaviridae family is the largest virus family consisting of more than 350 viruses. Despite the increasing knowledge regarding the biology of members of this family, little is known about Crimean-Congo hemorrhagic fever virus (CCHFV), a virus classified within the Nairovirus genus and the causative agent of a severe hemorrhagic fever in humans with high mortality. LÄS MER

  5. 5. Crimean-Congo hemorrhagic fever virus : interactions with host cell structures in viral replication

    Författare :Melinda Simon; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Crimean-Congo hemorrhagic fever virus (CCHFV) is a human pathogen, and was first associated with its corresponding disease during an outbreak in the mid 1940s. At that time, outbreaks were mainly restricted to the former Soviet Union, Africa and Asia, but lately disease incidents have markedly risen and CCHFV is now also endemic in several countries in the Middle East and Europe. LÄS MER