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Visar resultat 1 - 5 av 20 avhandlingar som matchar ovanstående sökkriterier.
1. Coxsackievirus B3 Infection and Host Defence Responses Change the Metabolism of PBDE
Sammanfattning : It has been suggested that the rising amounts of chemicals in the environment may affect host resistance and increase susceptibility to infections. Studies have also shown that infections can change the toxicity of pollutants. LÄS MER
2. Arsenic Influences Virus Replication in Experimental Coxsackievirus B3 Infection
Sammanfattning : Trace elements are essential for the host defence against infections, and during common infections, the balance of trace elements is changed in serum and tissues. Supplementation with selenium (Se), an essential trace element, is known to decrease the severity of coxsackievirus B3 (CVB3) infection in mice. LÄS MER
3. Effects of Enterovirus Infection on Innate Immunity and Beta Cell Function in Human Islets of Langerhans
Sammanfattning : This thesis focuses on enteroviral effects on human pancreatic islets. Most knowledge of viral effects on host cells relies on studies of immortalized cell lines or animal models. The islets represent a fundamentally different and less well studied cellular host. Also, enterovirus has been implicated in the etiology of type 1 diabetes (T1D). LÄS MER
4. Reverse genetic studies of Enterovirus replication
Sammanfattning : Enteroviruses belong to the Picornaviridae family and are small icosahedral viruses with RNA genomes of positive polarity, containing a single open reading frame. They mostly cause mild or asymptomatic infections, but also a wide array of diseases including: poliomyelitis, encephalitis, gastroenteritis, aseptic meningitis, myocarditis, hand-foot-and-mouth disease, hepatitis and respiratory diseases, ranging from severe infections to the common cold. LÄS MER
5. Characterization of the cellular receptor for coxsackievirus and adenovirus
Sammanfattning : CAR, the cellular receptor for coxsackievirus and adenovirus, was discovered in 1997. CAR is an evolutionary conserved transmembrane protein that belongs to the CTX subfamily within the large immunoglobulin superfamily. At the intracellular tail, CAR has a PDZ domain binding motif suggesting that CAR is part of a larger protein complex. LÄS MER