Sökning: "covalent modification"

Visar resultat 16 - 20 av 60 avhandlingar innehållade orden covalent modification.

  1. 16. A Novel Route for Construction of Multipurpose Receptors through Chemical Modification of Glutathione Transferases

    Författare :Johan Viljanen; Bengt Harald Jonsson; Kerstin Broo; Sophia Hober; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Human GST A1-1; site-specific covalent modification; tyrosine 9; lysine 216; methionine 208; multipurpose receptor; pattern recognition; protein purification; Chemistry; Kemi;

    Sammanfattning : This thesis describes how the human Alpha class glutathione transferase (GST) A1-1 can be reprogrammed either to function as a multipurpose biosensor for detection of small molecule analytes, or as a handle providing for more efficient protein purification.A novel, user-friendly, and efficient method for site-specific introduction of functional groups into the active site of hGST A1-1 is the platform for these achievements. LÄS MER

  2. 17. Surface Modification of Cellulose by Covalent Grafting and Physical Adsorption for Biocomposite Applications

    Författare :Carl Bruce; Eva Malmström; Anna Carlmark; Linda Fogelström; Youssef Habibi; KTH; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Kemi; Chemistry;

    Sammanfattning : There is an increasing interest to replace fossil-based materials with renewable alternatives. Cellulose fibers/nanofibrils (CNF) are sustainable options since they are biobased and biodegradable. In addition, they combine low weight with high strength; making them suitable to, for example, reinforce composites. LÄS MER

  3. 18. Catalysis and Site-Specific Modification of Glutathione Transferases Enabled by Rational Design

    Författare :Sofia Håkansson Hederos; Lars Baltzer; Kerstin Broo; Linköpings universitet; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Catalysis; Glutathione Transferases; Rational design; Protein design; Site-specific modification; thiolester hydrolysis; Enzyme engineering; Enzymteknik;

    Sammanfattning : This thesis describes the rational design of a novel enzyme, a thiolester hydrolase, derived from human glutathione transferase (GST) A1-1 by the introduction of a single histidine residue. The first section of the thesis describes the design and the determination of the reaction mechanism. LÄS MER

  4. 19. Carbon Nanostructures – from Molecules to Functionalised Materials : Fullerene-Ferrocene Oligomers, Graphene Modification and Deposition

    Författare :Michael Nordlund; Helena Grennberg; Mogens Brøndsted Nielsen; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Fullerenes; Graphene; Deposition; Functionalization; Organometallic complexes; Chemistry with specialization in Organic Chemistry; Kemi med inriktning mot organisk kemi;

    Sammanfattning : The work described in this thesis concerns development, synthesis and characterisation of new molecular compounds and materials based on the carbon allotropes fullerene (C60) and graphene.A stepwise strategy to a symmetric ferrocene-linked dumbbell of fulleropyrrolidines was developed. LÄS MER

  5. 20. Chemical Modification of Nanostructured Wood for Functional Biocomposites

    Författare :Shennan Wang; Qi Zhou; Gustav Nyström; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Wood; nanostructured materials; nanocellulose; delignification; oxidation; crosslinking; amination; MOFs; transparent film; hydrogel; aerogel; biocomposites; mechanical properties; thermochromic materials; CO2 capture; protein immobilization.; Biotechnology; Bioteknologi;

    Sammanfattning : Recently emerged top-down processing concept has provided new insights into the chemical modification of wood at the nanoscale. Nanostructured wood with naturally aligned cellulose microfibrils, cell wall nanoporosity, and precisely tuned chemical composition has opened up numerous possibilities for advanced design of functional materials. LÄS MER