Sökning: "coupled columns"

Visar resultat 1 - 5 av 10 avhandlingar innehållade orden coupled columns.

  1. 1. Bioanalysis of drugs and metabolites by liquid chromatography using coupled columns or post-column derivatization

    Författare :Margareta Johansson; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; PHARMACY; FARMACI;

    Sammanfattning : .... LÄS MER

  3. 2. Primary Recovery of Biologically Active Compounds Using Macroporous Monolithic Hydrogels

    Författare :Amro Hanora; Bioteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Downstream processing; macroporous; Biologically active compounds; Biotechnology; Läkemedelsteknik och relaterad teknik; Pharmaceutical and related technologies; Polymerteknik; biopolymers; Biokemisk teknik; Polymer technology; Makromolekylär kemi; Biochemical technology; Affinity chromatography; Ion exchange chromatography; Expanded bed adsorption chromatography.; Macromolecular chemistry; High through put screening; lactica acids; Endotoxin; Plasmid DNA; Cryogel columns; Bioteknik;

    Sammanfattning : The completion of sequencing of human and other mammalian genomes opens a new era for drug development. New approaches have been proposed for tackling diseases such as development of small molecule therapies based on understanding of human genome and proteome, new proteinous based therapies, where the therapeutic protein can inhibit or modify a certain metabolic pathway or DNA-based therapies delivering a gene into the cell (e. LÄS MER

  4. 3. Development of techniques and methods for drug analysis by packed capillary liquid chromatography with octadecylbonded silica and porous graphitic carbon columns

    Författare :Pernilla Koivisto; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Chemistry; Kemi; Chemistry; Kemi; Analytical Chemistry; analytisk kemi;

    Sammanfattning : Packed capillary liquid chromatography in combination with ultraviolet and mass spectrometric (MS) detection was explored as an analytical tool for drug analysis. The focus was put on column and sample preparation techniques as well as on fundamental aspects and development of chromatographic separations. LÄS MER

  5. 4. Developing integrated downstream processes for next-generation biologics

    Författare :Anton Löfgren; Avdelningen för kemiteknik; []
    Nyckelord :TEKNIK OCH TEKNOLOGIER; ENGINEERING AND TECHNOLOGY; Downstream processing; Preparative chromatography; Optimization; Integration;

    Sammanfattning : Manufacturing of biopharmaceuticals is a costly and time consuming process due to its inherent complexity and variability. The downstream process is the most expensive part and it involves multiple non-trivial steps. Continuous integrated manufacturing is a new concept that is encouraged by authorities. LÄS MER

  7. 5. Properties of some chlorinated polycyclic aromatic hydrocarbons with respect to chemical analysis

    Författare :Ulrika Nilsson; Stockholms universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES;

    Sammanfattning : This thesis describes chemical and biological properties of chloro-added and chloro-substituted PAHs with respect to chemical analysis. The work includes biological testing with Ames assay, study of chemical reactivities in chlorination reactions and retention characteristics on normal phase stationary phases for HPLC, as well as analysis of urban air samples with respect to chlorinated PAHs (Cl-PAHs). LÄS MER