Sökning: "cortisone"

Visar resultat 1 - 5 av 21 avhandlingar innehållade ordet cortisone.

  1. 1. Diagnosing hyper- and hypocortisolism using saliva samples : pitfalls and how to avoid them

    Författare :Nils Bäcklund; Per Dahlqvist; Göran Brattsand; Tommy Olsson; Elisabeth Aardal; Kerstin Landin-Wilhelmsen; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Cushing s syndrome; Adrenal Insufficiency; Salivary cortisol; Salivary cortisone; Reference intervals; Diagnostic accuracy; Error sources; invärtesmedicin; Internal Medicine; medicinsk biokemi; Medical Biochemistry;

    Sammanfattning : Background: Cushing's syndrome (CS) is caused by high cortisol secretion whereas insufficient cortisol secretion is called adrenal insufficiency (AI). Both are rare diseases with substantial diagnostic delay, and high morbidity and mortality even though effective treatment is available. LÄS MER

  3. 2. The role of steroid hormones in skeletal muscle metabolism

    Författare :Firoozeh Salehzadeh; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Steroid hormones play important roles in the regulation of whole body metabolism. Skeletal muscle is an insulin-responsive organ with a key role in overall substrate metabolism. Disturbances in skeletal muscle metabolism, as a result of hormonal imbalance may be an underlying defect in metabolic disease. LÄS MER

  4. 3. Congenital adrenal hyperplasia, CYP21 deficiency, screening and clinical aspects

    Författare :Anna Nordenström; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Congenital adrenal hyperplasia; 21 -hydroxylase deficiency; CYP21; neonatal screening; 17-OHP; sex-typed behavior; toy play.;

    Sammanfattning : Congenital adrenal hyperplasia (CAH) is a group of recessively inherited disorders. More than 90% of all cases of CAB are caused by 21-hydroxylase deficiency. This enzyme deficiency results in reduced ability to synthesize cortisol and aldosterone and at the same time increased secretion of androgens. LÄS MER

  5. 4. Molecular regulators of glucose and lipid metabolism in skeletal muscle

    Författare :Sameer S Kulkarni; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Skeletal muscle is a primary site of insulin action and insulin-stimulated glucose transport and occupies a center stage in maintaining whole body glucose and lipid homeostasis. Another key feature of a healthy skeletal muscle is its ability to switch between utilization of lipids and glucose as fuel in response to feeding or fasting respectively. LÄS MER

  7. 5. Studies on expression and regulation of phospholipase A2 and cyclooxygenase 2 in gastrointestinal tissues with special reference to colorectal cancer

    Författare :Jan Dimberg; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The phospholipases A2 (PLA2s) are phospholipid hydrolyzing enzymes that in mammalian cells exist in several different isoform including cytosolic PLA2 (cPLA2), group I PLA2 (PLA2-I) and group II PLA2 (PLA2-ll). PLA2 is involved in production of inflammatory mediators, membrane remodelling, digestive functions and stimulation of prolifemtion. LÄS MER