Sökning: "cortical"

Visar resultat 1 - 5 av 503 avhandlingar innehållade ordet cortical.

  1. 1. Generation of cortical neurons through reprogramming technology

    Författare :Giedre Miskinyte; Lund Neurologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICAL AND HEALTH SCIENCES; Cortex; Reprogramming; human ES cells; transcription factor programming; cortical projection neurons; Human adult cortical slices;

    Sammanfattning : The human cortex is affected by several debilitating acute and chronic neurodegenerative disorders such as stroke, traumatic brain injury, amyotrophic lateral sclerosis and Alzheimer’s disease, which target specific types of cortical neurons. Emerging evidence indicates that stem cells and reprogrammed cells can be used to generate human cortical neurons both for cell replacement by transplantation, and for disease modeling and drug screening. LÄS MER

  2. 2. Postischaemic superficial renal cortical microcirculation : experimental studies in the pig performed by laser Doppler flowmetry and measurement of tissue oxygenation

    Författare :Rolf Sandin; Uppsala universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : .... LÄS MER

  3. 3. Active Memory Processing on Multiple Time-scales in Simulated Cortical Networks with Hebbian Plasticity

    Författare :Florian Fiebig; Anders Lansner; Tim Vogels; KTH; []
    Nyckelord :NATURAL SCIENCES; NATURVETENSKAP; NATURVETENSKAP; NATURAL SCIENCES; Working memory; Long-term memory; consolidation; spiking; neural network; BCPNN; cortical microcircuit; Tillämpad matematik och beräkningsmatematik; Applied and Computational Mathematics; Biologisk fysik; Biological Physics;

    Sammanfattning : This thesis examines declarative memory function, and its underlying neural activity and mechanisms in simulated cortical networks. The included simulation models utilize and synthesize proposed universal computational principles of the brain, such as the modularity of cortical circuit organization, attractor network theory, and Hebbian synaptic plasticity, along with selected biophysical detail from the involved brain areas to implement functional models of known cortical memory systems. LÄS MER

  4. 4. Affective touch throughout life: from cortical processing in infancy to touch perception in adulthood

    Författare :Emma H. Jönsson; Göteborgs universitet; Göteborgs universitet; Gothenburg University; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Affective touch; Touch perception; Cortical activation; C-tactile afferents;

    Sammanfattning : Affective, interpersonal touch is important for forming and maintaining social bonds. In the hairy skin of humans there is a specific type of nerve fibers called C-tactile (CT) afferents which are optimally activated by a light stroking of the skin, like a caress. LÄS MER

  5. 5. Propofol changes the cytoskeletal function in neurons : An experimental study in cortical cultures

    Författare :Dean Turina; Christina Eintrei; Karin Björnström Karlsson; Lindahl Sten; Linköpings universitet; []
    Nyckelord :MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; Propofol; cytoskeleton;

    Sammanfattning : Every day, general anaesthetics are given to a large number of patients around the world but the cellular mechanisms of how anaesthetics act are still not clear. General anaesthetics cause the intended unconsciousness, amnesia and immobility in patients, but also side effects such as a decrease in mean arterial pressure and arrhythmia, both of which contribute to complications such as heart damage and stroke. LÄS MER