Sökning: "cor promoter"

Hittade 3 avhandlingar innehållade orden cor promoter.

  1. 1. Nuclear receptor corepressor N-CoR : role in transcriptional repression

    Författare :Kristina Loinder; Mats Söderström; Eckardt Treuter; Linköpings universitet; []
    Nyckelord :MEDICINE; MEDICIN;

    Sammanfattning : The human body consists of a multitude of cells of varying appearance and function. With a few exceptions they are genetically identical, and the key to their divergence lies in their different specific patterns of gene expression. LÄS MER

  3. 2. Hepatitis B virus infection and genomic changes from a long-term perspective

    Författare :Jonas Bläckberg; Sektion III; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Infektioner; Infections; cor promoter; precore; occult infection; HBV; mutation;

    Sammanfattning : Hepatitis B virus is a non-cytopathic virus with a small, circular, partially double-stranded DNA of 3.2 kb. It causes acute and chronic inflammatory liver disease and hepatocellular carcinoma (HCC). Retesting of stored sera from an outbreak of acute hepatitis in 1969-72 allowed identification of 126 cases of acute hepatitis B. LÄS MER

  4. 3. Molecular mechanisms of transcriptional repression by the orphan receptor SHP

    Författare :Ann Båvner; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Nuclear receptor; repression; small heterodimer partner; co-regulator;

    Sammanfattning : SHP (Small Heterodimer Partner) is an atypical orphan member of the mammalian nuclear receptor family that consists of only a putative ligand-binding domain and thus cannot bind DNA. The aim of this thesis was to investigate the molecular mechanisms of the transcriptionally inhibitory effect of SHP. LÄS MER