Sökning: "copy"

Visar resultat 1 - 5 av 900 avhandlingar innehållade ordet copy.

  1. 1. Modelling Allelic and DNA Copy Number Variations using Continuous-index Hidden Markov Models

    Författare :Susann Stjernqvist; Matematisk statistik; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Hidden Markov models; DNA copy number; allelic copy number; Markov chain Monte Carlo;

    Sammanfattning : In human cells there are usually two copies of each chromosome, but in cancer cells abnormalities could exist. The differences consist of segments of chromosomes with an altered number of copies. There can be deletions as well as amplifications and the lengths of the segments can also vary. LÄS MER

  3. 2. Copy Number Analysis of Cancer

    Författare :Markus Mayrhofer; Anders Isaksson; Simon Tavaré; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; chromosomes; oncology; bioinformatics; Bioinformatik; Bioinformatics; Oncology; Onkologi; Clinical Genetics; Klinisk genetik;

    Sammanfattning : By accurately describing cancer genomes, we may link genomic mutations to phenotypic effects and eventually treat cancer patients based on the molecular cause of their disease, rather than generalizing treatment based on cell morphology or tissue of origin.Alteration of DNA copy number is a driving mutational process in the formation and progression of cancer. LÄS MER

  4. 3. Raphael's Madonna of the Goldfinch, Copies and the Abbey of Vallombrosa Reconsidered, appendix: 1867-70, the Vallombrosa Arguments in Letters and Publications

    Författare :Måns Holst-Ekström; Avdelningen för konsthistoria och visuella studier; []
    Nyckelord :HUMANIORA; HUMANITIES; Raphael; Vallombrosa; copy;

    Sammanfattning : An investigation concerning a group of paintings sharing a common motif. The motif is the Madonna with the infants Jesus and Saint John, the Infant Jesus holding a goldfinch. Rapahel's version of the painting, in the Uffizi, is discussed in relation to a similar version of the motif that appeared in Sweden in the 1990's.. LÄS MER

  5. 4. Konst med konst som motiv : parafrasens estetik i 1900-talets bildkonst

    Författare :Hans Örtegren; Umeå universitet; []
    Nyckelord :HUMANIORA; HUMANITIES; Paraphrase; quotation; allusion; copy; mimesis; intertextuality; 20th- century art; Pablo Picasso; Francis Bacon; Marcel Duchamp; René Magritte; Roy Lichtenstein;

    Sammanfattning : The subject of the thesis is 20th-century art about art. The intentions of the artist, the reference given in the work, and the reaction of the perceiver are all important factors in the definition of a paraphrase of art.A paraphrase is made by an artist with the intention of clearly alluding to earlier art. LÄS MER

  7. 5. Molecular mechanism of plasmid copy number control in Yersinia

    Författare :Tifaine Héchard; Helen Wang; Javier Pizarro-Cerda; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Yersinia pseudotuberculosis; plasmid copy number; T3SS; infection; ddPCR; Mikrobiologi; Microbiology;

    Sammanfattning : The ability of pathogenic bacteria to cause disease depends on various virulence mechanisms. The three pathogenic species of Yersinia use a type III secretion system (T3SS) to translocate effector proteins into host cells and disrupt the immune system. This T3SS is encoded on a 70kb, low-copy, virulence plasmid. LÄS MER