Sökning: "controlled clinical-trial"

Visar resultat 1 - 5 av 77 avhandlingar innehållade orden controlled clinical-trial.

  1. 1. Vitamin D deficiency in Northern Sweden : a cross-sectional study of an immigrant population at latitude 63° N, including an open partially randomized, controlled trial studying the effect of supplementation with different doses of cholecalciferol

    Författare :Lena Granlund; Eva Fhärm; Christer Andersson; Marie Lindkvist; Anna Ramnemark; Ingrid B Bergström; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; vitamin D deficiency; 25-hydroxyvitamin D; cross-sectional study; immigrant; muscle strength; grip strength; anxiety; depression; health related quality of life; clinical trial; cholecalciferol; family medicine; allmänmedicin;

    Sammanfattning : Background: Vitamin D is a prohormone that plays a key role in the calcium and phosphate balance and has physiological functions throughout the entire body. Vitamin D is supplied by exposure to ultraviolet light or by food. The prevalence of vitamin D deficiency in immigrants in Northern Sweden was unknown. LÄS MER

  2. 2. Nonparametric tests for comparing two treatments by using ordinal data

    Författare :Helen Wahlström; Elisabeth Svensson; Jan Lanke; Sture Holm; Örebro universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Statistik; change; clinical trial; Monte Carlo; ordered categorical data; paired data; permutation test; Pitman efficiency; power; stratification; ties; visual analogue scale; Wilcoxon-Mann-Whitney statistic; statistik; Statistics; Statistik; Statistics; Statistik;

    Sammanfattning : This thesis concerns four nonparametric tests for comparing two treatments in a randomized controlled clinical trial when the main response variable generates discrete or continuous ordinal data and measurements are made at baseline and follow-up. In the Wilcoxon-Mann-Whitney test (WMW) the baseline values are not taken into account at all, but in the other three tests both baseline and follow-up values are used. LÄS MER

  3. 3. Depression in teenagers and young adults : foundational studies of the new treatment paradigm TARA: Training for Awareness, Resilience, and Action

    Författare :Erik Ekbäck; Eva Henje Blom; Ida Blomqvist; Jenny Molin; Inga Dennhag; Thorbjörn Lundberg; Elizabeth McCauley; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Depression; adolescents; young adults; medical students; mental health; anxiety; psychological stress; qualitative research; randomization; yoga; mindfulness; psychotherapy; antidepressant drugs; biomarkers; clinical trial; feasibility studies; online intervention; reliability; validity; confirmatory factor analysis; measurement invariance; barn- och ungdomspsykiatri; Child and Youth Psychiatry;

    Sammanfattning : Introduction: Depression in adolescents and young adults is an increasing global health concern and available treatments are not convincingly effective. It is therefore important to develop and test novel treatments to improve treatment outcomes. LÄS MER

  4. 4. HAMLET - In vivo effects and mechanisms of tumor-cell death

    Författare :Lotta Gustafsson; immunologi och glykobiologi - MIG Avdelningen för mikrobiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Biomedicinska vetenskaper; Biomedical sciences; proteasome stress; HAMLET; human milk; tumor-cell death; clinical trial; rat xenograft model; skin papilloma; glioblastoma;

    Sammanfattning : HAMLET (human alpha-lactalbumin made lethal to tumor cells), a molecular complex derived from human milk, is an interesting new tool in cancer research since it induces programmed cell death in tumor cells while leaving normal, differentiated cells unharmed. The in vivo effects of HAMLET were studied in a rat xenograft model of human glioblastoma. LÄS MER

  5. 5. Studies of occlusal adjustment therapy in patients with craniomandibular disorders

    Författare :Danila Vallon; Lunds universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; controlled clinical trial.; Occlusal adjustment; treatment outcome; Odontology; stomatology; Odontologi;

    Sammanfattning : In the first part of this thesis, measurement and registration procedures of occlusal interferences and their inter and intraobserver variability were evaluated. In the second part of this thesis, the short and long-term effect of occlusal adjustment therapy was prospectively assessed in a controlled clinical trial in a selected group of 50 patients with myogeneous craniomandibular disorders (CMD). LÄS MER