Sökning: "contrast agents"

Visar resultat 11 - 15 av 248 avhandlingar innehållade orden contrast agents.

  1. 11. Degradation, Metabolism and Relaxation Properties of Iron Oxide Particles for Magnetic Resonance Imaging

    Författare :Karen Briley Saebo; Håkan Ahlström; Atle Bjørnerud; Michael Knopp; Uppsala universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Radiology; Magnetic Resonance Imaging; contrast agents; iron oxide particles; metabolism; relaxation mechanisms; Radiologisk forskning; Radiological research; Radiologisk forskning;

    Sammanfattning : Whereas the effect of size and coating material on the pharmacokinetics and biodistribution of iron oxide based contrast agents are well documented, the effect of these parameters on liver metabolism has never been investigated. The primary purpose of this work was to evaluate the effect of iron oxide particle size and coating on the rate of liver clearance and particle degradation using a rat model. LÄS MER

  3. 12. Bioanalysis using capillary electrophoresis and mass spectrometry : Applied on proteins, protein nanofibrils and polyvinyl alcohol microbubbles

    Författare :Leila Josefsson; Åsa Emmer; Ulrika Nilsson; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; : amyloid; capillary electrophoresis; contrast agents; detection; human blood plasma; ionic liquids; mass spectrometry; microbubbles; polyvinyl alcohol microbubbles; protein nanofibrils; proteins; Kemi; Chemistry;

    Sammanfattning : The sequencing of the genome of various species, including the human species, have led to increased understanding about how a protein structure is generated, and how specific structures are related to the proteins’ functionality. In paper I and II of this thesis, the folding of proteins in vitro to form hierarchical nanostructures, which in vivo often have a pathological effect, have been studied. LÄS MER

  4. 13. Non-invasive diagnostic methods of intracranial arteries

    Författare :Birgitta Ramgren; Lund Diagnostisk radiologi; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; intracranial aneurysms; endovascular treatment; follow-up; subarachnoid haemorrhage; digital subtraction angiography; magnetic resonance angiography; computed tomography angiography; technical aspects; contrast agents; image quality;

    Sammanfattning : Aims of this thesis were to compare the agreement of different magnetic resonance angiography(MRA) techniques and digital subtraction angiography (DSA) in follow-up of intracranial aneurysms treated with coils in order to select the best MRA method, to evaluate the impact of increased iodine concentration in contrast medium and decreased tube voltage on arterial attenuation and image quality in computed tomography angiography (CTA) of intracranial arteries, and finally to evaluate the diagnostic accuracy of CTA in non-traumatic subarachnoid haemorrhage (SAH) compared to DSA and to assess the arterial attenuation (HU) as an image quality factor in this aspect. Follow-up DSA and time-of-flight (TOF) MRA at 1. LÄS MER

  5. 14. Bioanalytical separation using capillary electrophoresis : Applications with microbubbles and proteins

    Författare :Leila Josefsson; Åsa Emmer; KTH; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Background electrolyte; capillary electrophoresis; contrast agents; electroosmotic flow; ethylammonium nitrate; ionic liquids; microbubbles; particles; polyvinyl alcohol microbubbles; and separation; Kemi; Chemistry;

    Sammanfattning : In this thesis the possibilities of using capillary electrophoresis as a separation technique for analysis of proteins and microbubbles is presented.A complete analytical process consists of five necessary steps of which one is the actual analysis step. For this step a suitable analytical technique is needed. LÄS MER

  7. 15. Colloidal synthesis of metal oxide nanocrystals and thin films

    Författare :Fredrik Söderlind; Per-Olov Käll; Kajsa Uvdal; Mats Johnsson; Linköpings universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; nanoparticles; synthesis; contrast agents; functionalization; thin films; Chemistry; Kemi;

    Sammanfattning : A main driving force behind the recent years’ immense interest in nanoscience and nanotechnology is the possibility of achieving new material properties and functionalities within, e.g., material physics, biomedicine, sensor technology, chemical catalysis, energy storing systems, and so on. LÄS MER