Sökning: "conditional knock-out"

Visar resultat 6 - 7 av 7 avhandlingar innehållade orden conditional knock-out.

  1. 6. Deciphering the transcriptional regulation code in colorectal cancer genome

    Författare :Jian Yan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Colorectal cancer (CRC) is the third most common cancer type to threaten life for both men and women in the developed world. The molecular mechanism of CRC is very complicated and involves changes in different categories of biological processes, among which a large number of mutations affecting either coding sequence of transcription factors (TFs) or their binding sites in genome are included. LÄS MER

  2. 7. Neuromodulation shapes interneuron communication in the mouse striatum

    Författare :Matthijs Constantijn Dorst; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : A proper understanding of cognition relies on detailed knowledge about the functional connectivity within and between brain areas. The striatum is generally regarded as the input structure to the basal ganglia, a group of subcortical nuclei that have been demonstrated to be involved in motor function and reward, amongst other functions. LÄS MER