Sökning: "complex disease"

Visar resultat 21 - 25 av 1465 avhandlingar innehållade orden complex disease.

  1. 21. Genetic Studies of Psoriasis and Psoriatic Arthritis

    Författare :Camilla Friberg; Göteborgs universitet; []
    Nyckelord :psoriasis; psoriatic arthritis; complex disease; autoimmune disease; linkage analysis; association analysis; PSOR5; 3q21; 5q31-32; SLC22A4; SLC22A5; CSTA; ZNF148; expression;

    Sammanfattning : Psoriasis and psoriatic arthritis are common chronic immune-mediated diseases of the skin and joints. Psoriasis affects approximately 2-3 % of the Caucasian population and about 30 % of all psoriasis patients develop psoriatic arthritis. LÄS MER

  3. 22. Serological and faecal biomarkers in inflammatory bowel disease

    Författare :Karin Amcoff; Jonas Halfvarson; Marie Carlsson; Hans Törnblom; Örebro universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Crohn s disease; ulcerative colitis; inflammatory bowel disease; faecal calprotectin; antibodies; eosinophils; ECP; EDN;

    Sammanfattning : The inflammatory bowel diseases (IBD), Crohn's disease and ulcerative colitis, are relapsing and remitting disorders characterised by chronic inflammation at various sites in the gastrointestinal tract, resulting in diarrhoea and abdominal pain. Neither the aetiology nor the pathophysiology is yet fully understood, and there is currently no cure. LÄS MER

  4. 23. The role of leptin in endothelial dysfunction and cardiovascular disease

    Författare :Manuel Cruz Gonzalez Garcia; Stefan Söderberg; Jan Engvall; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; leptin; obesity; endothelial dysfunction; cardiovascular disease; kardiologi; Cardiology;

    Sammanfattning : Objective:  Obesity has become the leading cause of mortality worldwide; however, the fundamental pathophysiology underlying this association remains unclear. The discovery of adipokines, i.e., cytokines produced by adipose cells (adipocytes), revealed that adipose tissue is a highly endocrine organ, thus opening new lines of investigation. LÄS MER

  5. 24. Understanding Complex Diseases and Disease Causative Agents : The Machine Learning way

    Författare :Zeeshan Khaliq; Jan Komorowski; Steven Bosinger; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; NATURVETENSKAP; NATURAL SCIENCES; Pathogens; Influenza A viruses; Human immunodeficiency virus; Simian immunodeficiency virus; Pathogenicity; Cancer; long noncoding RNAs; Machine learning; Host specificity; Host-specific signatures; Bioinformatics; Bioinformatik;

    Sammanfattning : Diseases can be caused by foreign agents – pathogens – such as viruses, bacteria and other parasites, entering the body or by an internal malfunction of the body itself. The partial understanding of diseases like cancer and the ones caused by viruses, like the influenza A viruses (IAVs) and the human immunodeficiency virus, means we still do not have an efficient cure or defence against them. LÄS MER

  7. 25. Functional brain imaging of cognitive status in Parkinson's disease

    Författare :Urban Ekman; Johan Eriksson; Lars Nyberg; Lars Forsgren; Oury Monchi; Umeå universitet; []
    Nyckelord :MEDICIN OCH HÄLSOVETENSKAP; MEDICAL AND HEALTH SCIENCES; Parkinson’s disease; functional MRI; Mild cognitive impairment; Working memory; Parkinson’s disease dementia; BOLD;

    Sammanfattning : Parkinson’s disease (PD) is next to Alzheimer’s disease (AD) the second most common neurodegenerative disease. PD has traditionally been characterised as a motor disorder, but more recent research has revealed that cognitive impairments are frequent. LÄS MER