Sökning: "complete linkage"

Visar resultat 21 - 25 av 39 avhandlingar innehållade orden complete linkage.

  1. 21. Assessing future effects on lake ecosystem resilience using data analysis and dynamic modelling : Modelling the effects of extreme weather events and climate warming on lakes

    Författare :Jorrit P. Mesman; Bastiaan W Ibelings; Stéphane Goyette; Don C Pierson; Karsten Rinke; Uppsala universitet; []
    Nyckelord :NATURVETENSKAP; NATURAL SCIENCES; Extreme events; Storms; Modelling; Climate change; Thermal structure; Phytoplankton;

    Sammanfattning : Extreme weather events can have short-term and long-term effects on lake thermal structure, nutrient dynamics, and community composition. Moreover, changes in lake variables induced by global climate change may influence the response and recovery of lake ecosystems to extreme weather events. LÄS MER

  3. 22. Basal lamina genes affected in leiomyomatosis and congenital muscular dystrophy : structure and mutation analyses of the collagen COL4A6 and laminin LAMA2 genes

    Författare :Xu Zhang; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : Basal laminae (basement membranes) are flexible thin sheets of specialized extracellular matrix separating organ cells from the underlying or surrounding connective tissues. They are found beneath epithelial and endothelial cells amd surrounding different cells, such as muscle fibers and nerves. LÄS MER

  4. 23. Variation at candidate gene loci and their fuctional importance in rodent models of ethanol dependence

    Författare :Karl Björk; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :;

    Sammanfattning : As genetic research has progressed, psychiatric disorders, including the addictions have emerged as moderately heritable. For alcoholism, the overall heritability has been estimated from twin studies to range between 50 to 60%. LÄS MER

  5. 24. Exposures in utero and chronic disease : an alternative methodological approach

    Författare :Anna Hübinette; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Cardiovascular disease; acute myocardial infarction; angina pectoris; breast neoplasms; birth weight; birth anthropometrics; twin study; epidemiology; etiology; risk factors; insulin-like growth factors; preeclampsia; longitudinal study.;

    Sammanfattning : The aims of this thesis were to evaluate maternal and birth characteristics as risk factors for breast cancer and cardiovascular disease later in life, and to assess maternal serum concentrations of insulin-like growth factors in pregnancies complicated by preeclampsia. Birth characteristics and risks of breast cancer were studied in a case-control study nested within the population-based Swedish Twin Register (Paper 1). LÄS MER

  7. 25. Trinucleotide repeats and neuropsychiatric phenotypes

    Författare :Qiu-Ping Yuan; Karolinska Institutet; Karolinska Institutet; []
    Nyckelord :Trinucleotide; repeat expansion; psychiatric disorder; gene; spastic paraplegia;

    Sammanfattning : Genetic studies of affective disorders have yielded several chromosomal regions suggestive for linkage. Linkage analysis was performed in five families with unipolar affective disorder, collected from northern Sweden. Four candidate regions on chromosomes 16, 18, 21 and 4p were excluded. LÄS MER